KDM8

Gene Symbol KDM8
Entrez Gene 79831
Alt Symbol JMJD5
Species Human
Gene Type protein-coding
Description lysine (K)-specific demethylase 8
Other Description jmjC domain-containing protein 5|jumonji domain containing 5|jumonji domain-containing protein 5|lysine-specific demethylase 8
Swissprots Q9H8B1 B4DLU9 Q8N371 Q6VAK5
Accessions EAW55759 Q8N371 AK023860 BAB14706 AK225066 AK297166 BAG59661 AK298410 BAG60638 AK308499 AK310885 AY345239 AAQ23080 BC027911 AAH27911 BQ022832 DA497245 JF432533 ADZ15750 XM_006721092 XP_006721155 XM_011545950 XP_011544252 XM_011545951 XP_011544253 NM_001145348 NP_001138820 NM_024773 NP_079049
Function Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation. {ECO:0000269|PubMed:20457893}.
Subcellular Location Nucleus {ECO:0000269|PubMed:20457893}.
Tissue Specificity Weakly expressed in most cells. Highly expressed in breast cancer cells. {ECO:0000269|PubMed:20457893}.

JMJD5 (D-5) - sc-377078 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
JMJD5 (D-5): sc-377078. Western blot analysis of JMJD5 expression in non-transfected: sc-117752 (A) and mouse JMJD5 transfected: sc-127027 (B) 293T whole cell lysates.

JMJD5 (K-20) - sc-69428 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
JMJD5 (K-20): sc-69428. Immunoperoxidase staining of formalin fixed, paraffin-embedded human salivary gland tissue showing cytoplasmic and nuclear staining of glandular cells.

JMJD5 (G-3) - sc-377440 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
JMJD5 (G-3): sc-377440. Western blot analysis of JMJD5 expression in non-transfected: sc-117752 (A) and mouse JMJD5 transfected: sc-127027 (B) 293T whole cell lysates.

JMJD5 (Y-20) - sc-69429 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
JMJD5 (Y-20): sc-69429. Western blot analysis of JMJD5 expression in non-transfected: sc-117752 (A) and mouse JMJD5 transfected: sc-127027 (B) 293T whole cell lysates.

JMJD5 (H-21) - sc-133701 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
JMJD5 (H-21): sc-133701. Western blot analysis of JMJD5 expression in human fetal liver tissue extract.

Anti-JMJD5 antibody - ab106391 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-JMJD5 antibody (ab106391) at 1 µg/mlLane 2 : Anti-JMJD5 antibody (ab106391) at 2 µg/mlLane 1 : Human liver tissue lysateLane 2 : Human liver tissue lysateLysates/proteins at 15 µg per lane.

Anti-JMJD5 antibody - ab83011 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ChIP analysis using ab83011 (0.5µg/mL) binding JMJD5 in human HCT116 colon cancer cells. Without (- peptide) and with (+ peptide) blocking peptide. Protein binding was detected using real-time PCR.

Anti-JMJD5 antibody - ab36104 from Abcam

Prices $242.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-JMJD5 antibody - ab113673 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-JMJD5 antibody (ab113673) at 1 µg/mlLane 2 : Anti-JMJD5 antibody (ab113673) at 2 µg/mlLane 1 : Human liver tissue lysateLane 2 : Human liver tissue lysate

Anti-JMJD5 antibody - ab169579 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-JMJD5 antibody (ab169579) at 1 µg/mlLane 1 : JMJD5-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-JMJD5 antibody - ab28883 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-JMJD5 antibody (ab28883) at 0.5 µg/ml + Human Fetal Liver LysateSecondaryHRP conjugated anti-Rabbit IgG (suggested dilution 1:50,000 - 100,000)developed using the ECL technique

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (aa36-63, AP) - LS-C215322 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (aa36-63, APC) - LS-C215323 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (aa36-63, Biotin) - LS-C215324 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (aa36-63, FITC) - LS-C215325 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (C-Terminus) - LS-C29902 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal Liver Lysate

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (aa36-63, Azide-free, HRP) - LS-C215326 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (aa36-63, PE) - LS-C215327 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (C-Terminus, AP) - LS-C219843 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (aa72-121) - LS-C102749 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
JMJD5 antibody LS-C102749 Western blot of Fetal Liver lysate.

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (C-Terminus, APC) - LS-C219844 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (C-Terminus, FITC) - LS-C219845 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (C-Terminus, Biotin) - LS-C219846 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (C-Terminus, Azide-free, HRP) - LS-C219847 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM8 / JMJD5 / FLJ13798 Antibody (C-Terminus, PE) - LS-C219848 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more