KDM8

Gene Symbol	KDM8
Entrez Gene	79831
Alt Symbol	JMJD5
Species	Human
Gene Type	protein-coding
Description	lysine (K)-specific demethylase 8
Other Description	jmjC domain-containing protein 5|jumonji domain containing 5|jumonji domain-containing protein 5|lysine-specific demethylase 8
Swissprots	Q9H8B1 B4DLU9 Q8N371 Q6VAK5
Accessions	EAW55759 Q8N371 AK023860 BAB14706 AK225066 AK297166 BAG59661 AK298410 BAG60638 AK308499 AK310885 AY345239 AAQ23080 BC027911 AAH27911 BQ022832 DA497245 JF432533 ADZ15750 XM_006721092 XP_006721155 XM_011545950 XP_011544252 XM_011545951 XP_011544253 NM_001145348 NP_001138820 NM_024773 NP_079049
Function	Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation. {ECO:0000269|PubMed:20457893}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:20457893}.
Tissue Specificity	Weakly expressed in most cells. Highly expressed in breast cancer cells. {ECO:0000269|PubMed:20457893}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-JMJD5-cDNA-Clone - DC05702 from Abgent, a WuXi AppTec company Prices $561.60 Sizes 10 µg Species Human Accession BC027911

JMJD5 - MBS1278979 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC027911

Human JMJD5 ORF Clone(NM_001145348.1) - CDCL167580 from Creative Biomart Species Human Accession NM_001145348.1

Human JMJD5 ORF Clone(NM_024773.2) - CDCL167581 from Creative Biomart Species Human Accession NM_024773.2

Human KDM8 cDNA clone(NM_001145348.1) - CDFH009748 from Creative Biomart Species Human Accession NM_001145348.1

Human KDM8 ORF clone(NM_024773.2) - CDCR005096 from Creative Biomart Species Human Accession NM_024773.2

Human KDM8 ORF Clone(NM_001145348.1) - CDCR352743 from Creative Biomart Species Human Accession NM_001145348.1

Human KDM8 ORF Clone(NM_001145348.1) - CDCR352744 from Creative Biomart Species Human Accession NM_001145348.1

Human JMJD5/KDM8 Gene ORF cDNA clone in cloning vector - HG14451-G from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14451-NM from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, N-His tag - HG14451-NH from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14451-CM from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14451-ANG from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14451-NY from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14451-ACG from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, C-His tag - HG14451-CH from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid - HG14451-UT from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14451-ACR from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14451-ANR from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14451-CY from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14451-NF from Sino Biological Species Human

Human JMJD5/KDM8 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14451-CF from Sino Biological Species Human

Mouse KDM8 ORF clone (NM_001145348.1) - CDCL123665 from Creative biogene Species Human

Human KDM8 ORF clone (NM_024773.2) - CDCL123667 from Creative biogene Species Human

Human KDM8 ORF Clone (BC027911) - CDCS418821 from Creative biogene Species Human Accession Q8N371

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