KDM8

Gene Symbol	KDM8
Entrez Gene	79831
Alt Symbol	JMJD5
Species	Human
Gene Type	protein-coding
Description	lysine (K)-specific demethylase 8
Other Description	jmjC domain-containing protein 5|jumonji domain containing 5|jumonji domain-containing protein 5|lysine-specific demethylase 8
Swissprots	Q9H8B1 B4DLU9 Q8N371 Q6VAK5
Accessions	EAW55759 Q8N371 AK023860 BAB14706 AK225066 AK297166 BAG59661 AK298410 BAG60638 AK308499 AK310885 AY345239 AAQ23080 BC027911 AAH27911 BQ022832 DA497245 JF432533 ADZ15750 XM_006721092 XP_006721155 XM_011545950 XP_011544252 XM_011545951 XP_011544253 NM_001145348 NP_001138820 NM_024773 NP_079049
Function	Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation. {ECO:0000269|PubMed:20457893}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:20457893}.
Tissue Specificity	Weakly expressed in most cells. Highly expressed in breast cancer cells. {ECO:0000269|PubMed:20457893}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human JMJD5 full length protein - ab132413 from Abcam Category Protein Source Wheat germ Species Human

Human JMJD5 peptide - ab36103 from Abcam Category Peptide

KDM8 / JMJD5 / FLJ13798 Antibody Blocking Peptide - LS-E646 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KDM8 / JMJD5 / FLJ13798 Antibody Blocking Peptide - LS-E30769 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

KDM8 / JMJD5 / FLJ13798 Antibody Blocking Peptide - LS-E11877 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KDM8 / JMJD5 / FLJ13798 Antibody Blocking Peptide - LS-E21265 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

JMJD5 Recombinant Protein - H00079831-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

JMJD5 Blocking Peptide - NBP1-77074PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

JMJD5-Antibody-N-term-Blocking-peptide - BP10986a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

JMJD5 Peptide - GTX85251-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

JMJD5 Blocking Peptide - 33R-1191 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

JMJD5 Blocking Peptide - 33R-4751 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

JMJD5 - H00079831-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

JMJD5 - H00079831-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

JMJD5 Control Peptide - AP30463CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

JMJD5 Peptide - 5381P from ProSci Category Peptide Species Human

JMJD5 fusion protein - ag15115 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

JMJD5 fusion protein - ag15256 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human JMJD5, GST-tagged - JMJD5-206H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Lysine-specific demethylase 8(JMJD5) - CSB-YP839789HU CSB-EP839789HU CSB-BP839789HU CSB-MP839789HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

JMJD5 (transcript variant 2) - TP306417 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

JMJD5 (transcript variant 1) - TP327709 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

JMJD5 Protein - NBP1-82249PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

JMJD5-Antibody-C-term-2-Blocking-Peptide - BP1031a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

JMJD5-Blocking-Peptide-C-term - BP1031b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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