KDM8

Gene Symbol KDM8
Entrez Gene 79831
Alt Symbol JMJD5
Species Human
Gene Type protein-coding
Description lysine (K)-specific demethylase 8
Other Description jmjC domain-containing protein 5|jumonji domain containing 5|jumonji domain-containing protein 5|lysine-specific demethylase 8
Swissprots Q9H8B1 B4DLU9 Q8N371 Q6VAK5
Accessions EAW55759 Q8N371 AK023860 BAB14706 AK225066 AK297166 BAG59661 AK298410 BAG60638 AK308499 AK310885 AY345239 AAQ23080 BC027911 AAH27911 BQ022832 DA497245 JF432533 ADZ15750 XM_006721092 XP_006721155 XM_011545950 XP_011544252 XM_011545951 XP_011544253 NM_001145348 NP_001138820 NM_024773 NP_079049
Function Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation. {ECO:0000269|PubMed:20457893}.
Subcellular Location Nucleus {ECO:0000269|PubMed:20457893}.
Tissue Specificity Weakly expressed in most cells. Highly expressed in breast cancer cells. {ECO:0000269|PubMed:20457893}.

JMJD5 CRISPR/Cas9 KO Plasmid (h) - sc-405787 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD5 HDR Plasmid (h) - sc-405787-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD5 Double Nickase Plasmid (h) - sc-405787-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD5 Double Nickase Plasmid (h2) - sc-405787-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD5 CRISPR Activation Plasmid (h) - sc-405787-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD5 CRISPR Activation Plasmid (h2) - sc-405787-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD5 Lentiviral Activation Particles (h) - sc-405787-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD5 Lentiviral Activation Particles (h2) - sc-405787-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD5 siRNA (h) - sc-75359 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JMJD5 shRNA Plasmid (h) - sc-75359-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JMJD5 shRNA (h) Lentiviral Particles - sc-75359-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU149061 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10868 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10868 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07814 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07814

KDM8 siRNA (Human) - CRJ2596 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human JMJD5 (NM_024773.2) - SHH322087 from Creative biogene

Category siRNA
Species Reactivities Human

JMJD5 CRISPR/Cas9 KO Plasmid (h2) - sc-405787-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD5 HDR Plasmid (h2) - sc-405787-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human KDM8 siRNA - orb273097 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KDM8 shRNA Plasmid (Human) - CHJ2596 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KDM8 miRNA 3'UTR clone - MiUTR3H-12207 from Creative biogene

Species Reactivities Human

KDM8 miRNA 3'UTR clone - MiUTR3H-12208 from Creative biogene

Species Reactivities Human
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