MGAT4B

Gene Symbol MGAT4B
Entrez Gene 11282
Alt Symbol GNT-IV, GNT-IVB
Species Human
Gene Type protein-coding
Description mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
Other Description N-acetylglucosaminyltransferase IVb|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb|UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV|UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb|alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B|alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase|aminyltransferase|glcNAc-T IVb|mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme B
Swissprots A8MPR0 Q9UQ53 Q96GH4 Q86TF1 Q9NSK6
Accessions EAW53788 EAW53789 EAW53790 EAW53791 EAW53792 EAW53793 EAW53794 EAW53795 Q9UQ53 AB000624 BAA83464 AK023137 BAG51162 AK225490 AK225492 AL162067 CAB82404 AL537522 AY358984 AAQ89343 BC009464 AAH09464 BC051835 AAH51835 BQ882570 BQ939735 CN369872 NM_014275 NP_055090 NM_054013 NP_463459
Function Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N- glycan biosynthesis.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed. Strongly overexpressed in pancreatic cancer. {ECO:0000269|PubMed:10372966}.
Top Pathways N-Glycan biosynthesis

GnT-IVB (Y-14) - sc-160387 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GnT-IVB (Y-14): sc-160387. Western blot analysis of GnT-IVB expression in SK-MEL-28 whole cell lysate.

GnT-IVB (C-15) - sc-160385 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GnT-IVB (N-13) - sc-160386 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-MGAT4B antibody - ab177206 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin-embedded Human kidney tissue labeling MGAT4B with ab177206 at 1/100 dilution.

Anti-MGAT4B antibody - ab196248 from Abcam

Prices $370.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MGAT4B antibody (ab196248) at 1/500 dilutionLane 1 : HepG2 cell lysateLane 2 : Human fetal kidney lysate

Anti-MGAT4B antibody - ab168485 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation of MGAT4B transfected lysate using ab168485 and Protein A Magnetic Beads, and immunoblotted with an anti-MGAT4B purified mouse polyclonal antibody.

Anti-MGAT4B Antibody - LS-C308970 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MGAT4B Antibody - LS-C311388 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MGAT4B Antibody (aa401-501) - LS-C308971 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

MGAT4B Antibody - NBP2-14236 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: MGAT4B Antibody [NBP2-14236] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

MGAT4B Antibody - H00011282-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: MGAT4B Antibody [H00011282-B01P] - Analysis of MGAT4B expression in transfected 293T cell line by MGAT4B polyclonal antibody. Lane 1: MGAT4B transfected lysate(61.93 KDa). Lane 2: Non-transfected lysate.

MGAT4B Antibody - H00011282-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

MGAT4B Antibody - H00011282-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MGAT4B antibody produced in mouse - SAB1407130 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MGAT4B: <B>Cat. No. SAB1407130</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~61.9 kDa using MGAT4B transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Monoclonal Anti-MGAT4B antibody produced in mouse - WH0011282M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F4

Anti-MGAT4B antibody produced in rabbit - HPA052134 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MGAT4B:<B>Cat. No. HPA052134</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

MGAT4B Antibody - abx036320 from Abbexa

Host Rabbit
Clonality Polyclonal

MGAT4B antibody - H00011282-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

MGAT4B antibody - H00011282-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of MGAT4B expression in transfected 293T cell line (H00011282-T01) by MGAT4B MaxPab polyclonal antibody. Lane 1: MGAT4B transfected lysate(61.93 KDa). Lane 2: Non-transfected lysate.

MGAT4B antibody - H00011282-D01 from Acris Antibodies

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MGAT4B antibody - H00011282-M01 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F4
MGAT4B monoclonal antibody (M01), clone 1F4. Western Blot analysis of MGAT4B expression in human pancreas.

MGAT4B antibody - 16308-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal

MGAT4B Antibody - 40011 from Signalway Antibody

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MGAT4B Antibody - E306936 from Enogene

Prices $275.00
Sizes 100ug/200ul

MGAT4B, Monoclonal Antibody - MBS6013192 from MyBioSource

Prices $580.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F4
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