MGAT4B

Gene Symbol	MGAT4B
Entrez Gene	11282
Alt Symbol	GNT-IV, GNT-IVB
Species	Human
Gene Type	protein-coding
Description	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
Other Description	N-acetylglucosaminyltransferase IVb|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb|UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV|UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb|alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B|alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase|aminyltransferase|glcNAc-T IVb|mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme B
Swissprots	A8MPR0 Q9UQ53 Q96GH4 Q86TF1 Q9NSK6
Accessions	EAW53788 EAW53789 EAW53790 EAW53791 EAW53792 EAW53793 EAW53794 EAW53795 Q9UQ53 AB000624 BAA83464 AK023137 BAG51162 AK225490 AK225492 AL162067 CAB82404 AL537522 AY358984 AAQ89343 BC009464 AAH09464 BC051835 AAH51835 BQ882570 BQ939735 CN369872 NM_014275 NP_055090 NM_054013 NP_463459
Function	Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N- glycan biosynthesis.
Subcellular Location	Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	Widely expressed. Strongly overexpressed in pancreatic cancer. {ECO:0000269|PubMed:10372966}.
Top Pathways	N-Glycan biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MGAT4B full length protein - ab161402 from Abcam Category Protein Source Wheat germ Species Human

Human MGAT4B protein fragment - ab161403 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human MGAT4B Protein - H00011282-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MGAT4B Protein - H00011282-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MGAT4B - H00011282-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MGAT4B - H00011282-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MGAT4B - H00011282-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MGAT4B - H00011282-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MGAT4B fusion protein - ag9293 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MGAT4B fusion protein - Ag9476 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltra - CSB-YP890781HU CSB-EP890781HU CSB-BP890781HU CSB-MP890781HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B(MGAT4B) - MBS1294488 from MyBioSource Category Protein Prices $2,225.00, $2,225.00, $2,690.00, $2,690.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

MGAT4B Protein - NBP2-14236PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MGAT4B-Blocking-Peptide-N-Term - BP22002a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MGAT4B Peptide, Human - M34GP09486H from Creative Peptides Category Peptide Source Synthetic. Species Human

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