MGAT4B

Gene Symbol	MGAT4B
Entrez Gene	11282
Alt Symbol	GNT-IV, GNT-IVB
Species	Human
Gene Type	protein-coding
Description	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
Other Description	N-acetylglucosaminyltransferase IVb|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb|UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV|UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb|alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B|alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase|aminyltransferase|glcNAc-T IVb|mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme B
Swissprots	A8MPR0 Q9UQ53 Q96GH4 Q86TF1 Q9NSK6
Accessions	EAW53788 EAW53789 EAW53790 EAW53791 EAW53792 EAW53793 EAW53794 EAW53795 Q9UQ53 AB000624 BAA83464 AK023137 BAG51162 AK225490 AK225492 AL162067 CAB82404 AL537522 AY358984 AAQ89343 BC009464 AAH09464 BC051835 AAH51835 BQ882570 BQ939735 CN369872 NM_014275 NP_055090 NM_054013 NP_463459
Function	Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N- glycan biosynthesis.
Subcellular Location	Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	Widely expressed. Strongly overexpressed in pancreatic cancer. {ECO:0000269|PubMed:10372966}.
Top Pathways	N-Glycan biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MGAT4B 293T Cell Transient Overexpression Lysate(Denatured) - H00011282-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

MGAT4B overexpression lysate - LY415400 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MGAT4B 293 Cell Lysate - 407254 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MGAT4B Overexpression Lysate (Denatured) - H00011282-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

MGAT4B Overexpression Lysate (Native) - NBL1-13055 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MGAT4B Over-expression Lysate Product - GWB-C64B5F from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human MGAT4B Knockdown Stable Cell Line - CSC-DC009486 from Creative biogene Category Cell Line Species Human

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