| Gene Symbol | KCNMB2 |
|---|---|
| Entrez Gene | 10242 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | potassium channel subfamily M regulatory beta subunit 2 |
| Other Description | BK channel beta subunit 2|BK channel subunit beta-2|MaxiK channel beta 2 subunit|MaxiK channel beta-subunit 2|big potassium channel beta subunit 2|calcium-activated potassium channel subunit beta-2|charybdotoxin receptor subunit beta-2|hCG1646471|hbeta2|k(VCA)beta-2|large conductance calcium-activated potassium channel beta 2 subunit|large-conductance Ca2+-activated K+ channel beta2 subunit|potassium large conductance calcium-activated channel, subfamily M, beta member 2|slo-beta-2 |
| Swissprots | Q9Y691 |
| Accessions | EAW78428 EAW78429 EAW78430 EAW78431 Q9Y691 AA904191 AB193524 BAG69602 AB193525 BAG69603 AB193526 BAG69604 AB193527 BAG69605 AB193528 BAG69606 AB193529 BAG69607 AB193530 BAG69608 AF099137 AAD23380 AF209747 AAF36562 AK298291 BAH12749 BC017825 AAH17825 BF434939 BG701449 BM983559 DA532966 DQ892011 ABM82937 DQ895200 ABM86126 XM_011512325 XP_011510627 XM_011512326 XP_011510628 XM_011512327 XP_011510629 XM_011512328 XP_011510630 NM_001278911 NP_001265840 NM_005832 NP_005823 NM_181361 NP_852006 |
| Function | Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons. {ECO:0000269|PubMed:10097176, ECO:0000269|PubMed:10377337}. |
| Subcellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues. {ECO:0000269|PubMed:10097176, ECO:0000269|PubMed:10377337, ECO:0000269|PubMed:10692449}. |
| Top Pathways | Vascular smooth muscle contraction, cGMP-PKG signaling pathway |
Calcium-activated potassium channel subunit beta-2 (KCNMB2), Human, ELISA Kit - E01C2316 from ARP American Research Products
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Calcium activated potassium channel subunit beta 2 (KCNMB2), ELISA Kit - MBS7235361 from MyBioSource
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Calcium-activated potassium channel subunit beta-2 (KCNMB2), ELISA Kit - MBS7234574 from MyBioSource
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Calcium-activated potassium channel subunit beta-2 (KCNMB2), ELISA Kit - MBS7238161 from MyBioSource
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Calcium-activated potassium channel subunit beta-2 (KCNMB2), ELISA Kit - MBS7219482 from MyBioSource
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Calcium-activated potassium channel subunit beta-2 (KCNMB2), ELISA Kit - MBS7213907 from MyBioSource
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Calcium-activated potassium channel subunit beta-2 (KCNMB2), ELISA Kit - MBS7201129 from MyBioSource
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Calcium-activated potassium channel subunit beta-2 (KCNMB2), ELISA Kit - MBS7228267 from MyBioSource
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Calcium-activated potassium channel subunit beta-2 (KCNMB2), ELISA Kit - MBS7204729 from MyBioSource
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Calcium-activated potassium channel subunit beta-2 (KCNMB2), ELISA Kit - MBS7247274 from MyBioSource
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Calcium-activated potassium channel subunit beta-2 (KCNMB2), ELISA Kit - MBS7203789 from MyBioSource
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Calcium-activated potassium channel subunit beta-2 (KCNMB2), ELISA Kit - MBS7225811 from MyBioSource
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Calcium-activated potassium channel subunit beta-2 (KCNMB2), ELISA Kit - MBS7252717 from MyBioSource
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Human KCNMB2 ELISA Kit - E005985 from Biobool
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anti-KCNMB2 antibody [S53-32] - ARG22284 from Arigo Biolaboratories
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