KCNMB2

Gene Symbol KCNMB2
Entrez Gene 10242
Alt Symbol -
Species Human
Gene Type protein-coding
Description potassium channel subfamily M regulatory beta subunit 2
Other Description BK channel beta subunit 2|BK channel subunit beta-2|MaxiK channel beta 2 subunit|MaxiK channel beta-subunit 2|big potassium channel beta subunit 2|calcium-activated potassium channel subunit beta-2|charybdotoxin receptor subunit beta-2|hCG1646471|hbeta2|k(VCA)beta-2|large conductance calcium-activated potassium channel beta 2 subunit|large-conductance Ca2+-activated K+ channel beta2 subunit|potassium large conductance calcium-activated channel, subfamily M, beta member 2|slo-beta-2
Swissprots Q9Y691
Accessions EAW78428 EAW78429 EAW78430 EAW78431 Q9Y691 AA904191 AB193524 BAG69602 AB193525 BAG69603 AB193526 BAG69604 AB193527 BAG69605 AB193528 BAG69606 AB193529 BAG69607 AB193530 BAG69608 AF099137 AAD23380 AF209747 AAF36562 AK298291 BAH12749 BC017825 AAH17825 BF434939 BG701449 BM983559 DA532966 DQ892011 ABM82937 DQ895200 ABM86126 XM_011512325 XP_011510627 XM_011512326 XP_011510628 XM_011512327 XP_011510629 XM_011512328 XP_011510630 NM_001278911 NP_001265840 NM_005832 NP_005823 NM_181361 NP_852006
Function Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons. {ECO:0000269|PubMed:10097176, ECO:0000269|PubMed:10377337}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues. {ECO:0000269|PubMed:10097176, ECO:0000269|PubMed:10377337, ECO:0000269|PubMed:10692449}.
Top Pathways Vascular smooth muscle contraction, cGMP-PKG signaling pathway

Human KCNMB2 full length protein - ab160899 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160899 on a 12.5% SDS-PAGE stained with Coomassie Blue.

KCNMB2 Antibody Blocking Peptide - LS-E12640 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human KCNMB2 Protein - H00010242-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

KCNMB2 Blocking Peptide - abx063658 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Bovine

KCNMB2 - H00010242-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

KCNMB2 - H00010242-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

KCNMB2 fusion protein - Ag9793 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human KCNMB2, His-tagged - KCNMB2-273H from Creative Biomart

Category Protein
Source E.coli
Species Human

KCNMB2 Blocking Peptide - CBP2464 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine

KCNMB2-Blocking-Peptide-N-term - BP20284a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

KCNMB2-Blocking-Peptide-N-term - BP21369a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

KCNMB2-Blocking-Peptide-C-term - BP21356b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

KCNMB2 Peptide, Human - M34GP07992H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

KCNMB2 peptide - orb218327 from Biorbyt

Category Peptide
Species Human, Mouse, Rat

Recombinant Human KCNMB2 Protein, GST-tagged - KCNMB2-033H from Creative Biomart

Category Protein
Source Wheat Germ
Species Human
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