KCNMB2

Gene Symbol KCNMB2
Entrez Gene 10242
Alt Symbol -
Species Human
Gene Type protein-coding
Description potassium channel subfamily M regulatory beta subunit 2
Other Description BK channel beta subunit 2|BK channel subunit beta-2|MaxiK channel beta 2 subunit|MaxiK channel beta-subunit 2|big potassium channel beta subunit 2|calcium-activated potassium channel subunit beta-2|charybdotoxin receptor subunit beta-2|hCG1646471|hbeta2|k(VCA)beta-2|large conductance calcium-activated potassium channel beta 2 subunit|large-conductance Ca2+-activated K+ channel beta2 subunit|potassium large conductance calcium-activated channel, subfamily M, beta member 2|slo-beta-2
Swissprots Q9Y691
Accessions EAW78428 EAW78429 EAW78430 EAW78431 Q9Y691 AA904191 AB193524 BAG69602 AB193525 BAG69603 AB193526 BAG69604 AB193527 BAG69605 AB193528 BAG69606 AB193529 BAG69607 AB193530 BAG69608 AF099137 AAD23380 AF209747 AAF36562 AK298291 BAH12749 BC017825 AAH17825 BF434939 BG701449 BM983559 DA532966 DQ892011 ABM82937 DQ895200 ABM86126 XM_011512325 XP_011510627 XM_011512326 XP_011510628 XM_011512327 XP_011510629 XM_011512328 XP_011510630 NM_001278911 NP_001265840 NM_005832 NP_005823 NM_181361 NP_852006
Function Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons. {ECO:0000269|PubMed:10097176, ECO:0000269|PubMed:10377337}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues. {ECO:0000269|PubMed:10097176, ECO:0000269|PubMed:10377337, ECO:0000269|PubMed:10692449}.
Top Pathways Vascular smooth muscle contraction, cGMP-PKG signaling pathway

KCNMB2 CRISPR/Cas9 KO Plasmid (h) - sc-411440 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNMB2 HDR Plasmid (h) - sc-411440-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNMB2 Double Nickase Plasmid (h) - sc-411440-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNMB2 Double Nickase Plasmid (h2) - sc-411440-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNMB2 CRISPR Activation Plasmid (h) - sc-411440-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNMB2 CRISPR Activation Plasmid (h2) - sc-411440-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNMB2 Lentiviral Activation Particles (h) - sc-411440-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNMB2 Lentiviral Activation Particles (h2) - sc-411440-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNMB2 siRNA (h) - sc-78123 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KCNMB2 shRNA Plasmid (h) - sc-78123-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KCNMB2 shRNA (h) Lentiviral Particles - sc-78123-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KCNMB2 RNAi - H00010242-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

KCNMB2 RNAi - H00010242-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU051781 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10978 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10978 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09601 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09601

KCNMB2 siRNA (Human) - CRH6929 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KCNMB2 (NM_181361.1) - SHH323551 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human KCNMB2(NM_005832.3) - SHL190738 from Creative biogene

Category siRNA
Species Reactivities Human

KCNMB2 shRNA Plasmid (Human) - CHH6929 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KCNMB2 miRNA 3'UTR clone - MiUTR1H-05155 from Creative biogene

Species Reactivities Human

KCNMB2 miRNA 3'UTR clone - MiUTR3H-07479 from Creative biogene

Species Reactivities Human
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