KCNMB2

Gene Symbol KCNMB2
Entrez Gene 10242
Alt Symbol -
Species Human
Gene Type protein-coding
Description potassium channel subfamily M regulatory beta subunit 2
Other Description BK channel beta subunit 2|BK channel subunit beta-2|MaxiK channel beta 2 subunit|MaxiK channel beta-subunit 2|big potassium channel beta subunit 2|calcium-activated potassium channel subunit beta-2|charybdotoxin receptor subunit beta-2|hCG1646471|hbeta2|k(VCA)beta-2|large conductance calcium-activated potassium channel beta 2 subunit|large-conductance Ca2+-activated K+ channel beta2 subunit|potassium large conductance calcium-activated channel, subfamily M, beta member 2|slo-beta-2
Swissprots Q9Y691
Accessions EAW78428 EAW78429 EAW78430 EAW78431 Q9Y691 AA904191 AB193524 BAG69602 AB193525 BAG69603 AB193526 BAG69604 AB193527 BAG69605 AB193528 BAG69606 AB193529 BAG69607 AB193530 BAG69608 AF099137 AAD23380 AF209747 AAF36562 AK298291 BAH12749 BC017825 AAH17825 BF434939 BG701449 BM983559 DA532966 DQ892011 ABM82937 DQ895200 ABM86126 XM_011512325 XP_011510627 XM_011512326 XP_011510628 XM_011512327 XP_011510629 XM_011512328 XP_011510630 NM_001278911 NP_001265840 NM_005832 NP_005823 NM_181361 NP_852006
Function Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons. {ECO:0000269|PubMed:10097176, ECO:0000269|PubMed:10377337}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues. {ECO:0000269|PubMed:10097176, ECO:0000269|PubMed:10377337, ECO:0000269|PubMed:10692449}.
Top Pathways Vascular smooth muscle contraction, cGMP-PKG signaling pathway

KCNMB2-Over-expression-Lysate - LY16340a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag KCNMB2 (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the KCNMB2 gene‘

KCNMB2 Lysate(Denatured) - H00010242-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

KCNMB2 293 Cell Lysate - 401584 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

KCNMB2 293 Cell Lysate - 403712 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

KCNMB2 Overexpression Lysate (Denatured) - H00010242-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
KCNMB2 transfected lysate.

KCNMB2 Overexpression Lysate (Native) - NBL1-12191 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: KCNMB2 Overexpression Lysate (Adult Normal) [NBL1-12191] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KCNMB2.

KCNMB2 Overexpression Lysate (Native) - NBL1-12192 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

KCNMB2 Over-expression Lysate Product - GWB-E48290 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

KCNMB2 Over-expression Lysate Product - GWB-4A86DD from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human KCNMB2 Knockdown Stable Cell Line - CSC-DC007992 from Creative biogene

Category Cell Line
Species Human
Search more