NCK2

Gene Symbol NCK2
Entrez Gene 8440
Alt Symbol GRB4, NCKbeta
Species Human
Gene Type protein-coding
Description NCK adaptor protein 2
Other Description SH2/SH3 adaptor protein NCK-beta|cytoplasmic protein NCK2|growth factor receptor-bound protein 4|noncatalytic region of tyrosine kinase, beta
Swissprots Q9BWN9 O43639 Q9UIC3 D3DVK1
Accessions AAY14937 AAY24332 EAX01753 EAX01754 O43639 AF043119 AAC04831 AF047487 AAC80284 BC000103 AAH00103 BC007195 AAH07195 BC033176 BG480643 BM555604 BM920530 BU738133 CB959523 DB456958 XM_006712797 XP_006712860 XM_011511991 XP_011510293 XM_011511992 XP_011510294 NM_001004720 NP_001004720 NM_001004722 NP_001004722 NM_003581 NP_003572
Function Adapter protein which associates with tyrosine- phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1- dependent transcriptional activation in response to activated Ras signaling. {ECO:0000269|PubMed:10026169, ECO:0000269|PubMed:16835242}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16835242}. Endoplasmic reticulum {ECO:0000269|PubMed:16835242}.
Tissue Specificity Ubiquitous.
Top Pathways Axon guidance, T cell receptor signaling pathway, Pathogenic Escherichia coli infection, ErbB signaling pathway

NCK2 (8.8) - sc-20020 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NCK2 (8.8): sc-20020. Immunofluorescence staining of methanol-fixed H4 cells (A) and immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast tumor (B) showing cytoplasmic staining.

NCK2 (V-14) - sc-22508 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Nck beta antibody - ab14590 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Nck beta antibody - ab183125 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling Nck beta with ab183125 at 1/60 dilution. The image on the right is treated with the synthesized peptide.

Anti-Nck beta antibody - ab58381 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab58381 at 1/50-1/100 dilution staining Nck beta in human colon carcinoma by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.

Anti-Nck beta antibody - ab88367 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Nck beta antibody (ab88367) at 1 µg/ml + Human spleen tissue lysate at 50 µg

Anti-Nck beta antibody - ab27431 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Nck beta antibody [AF3F11] - ab80618 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone AF3F11
All lanes : Anti-Nck beta antibody [AF3F11] (ab80618) at 1/2000 dilutionLane 1 : U937 cell lysateLane 2 : Hepg2 cell lysateLane 3 : A431 cell lysateLane 4 : K562 cell lysateLane 5 : SK-N-MC cell lysate

Anti-Nck beta antibody [EPR3333] - ab109239 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3333
Immunohistochemical analysis of paraffin-embedded human breast ductal carcinoma tissue using ab109239 at a dilution of 1/50

Anti-Nck beta antibody, prediluted - ab27432 from Abcam

Prices $370.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
ab27432, prediluted, staining Nck beta in paraffin embedded, formalin fixed human breast carcinoma by Immunohistochemistry.

Anti-Nck beta antibody - N-terminal - ab174859 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-Nck beta antibody - N-terminal (ab174859) at 1/1000 dilutionLane 1 : HeLa total cell extractLane 2 : Jurkat total cell extract

Anti-GRB4 / NCK2 Antibody (aa175-190) - LS-C25734 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-GRB4 / NCK2 Antibody (aa119-276) - LS-C50320 from LifeSpan Bioscience

Prices $440.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal
Human breast ca stained with Anti-NCK2

Anti-GRB4 / NCK2 Antibody (aa331-380) - LS-C118531 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human colon carcinoma tissue, using NCK2 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-GRB4 / NCK2 Antibody (aa62-92, APC) - LS-C264088 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRB4 / NCK2 Antibody (aa62-92, AP) - LS-C264087 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRB4 / NCK2 Antibody (aa62-92, Biotin) - LS-C264090 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRB4 / NCK2 Antibody (aa62-92, Azide-free, HRP) - LS-C264092 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRB4 / NCK2 Antibody (aa62-92, PE) - LS-C264094 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRB4 / NCK2 Antibody (aa62-92, FITC) - LS-C264091 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRB4 / NCK2 Antibody (aa62-92) - LS-C329875 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRB4 / NCK2 Antibody - LS-C155315 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: A549 7.5% SDS PAGE NCK2 antibody diluted at 1:10000

Anti-GRB4 / NCK2 Antibody (Ile364) - LS-C176331 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of NCK2 (I364) pAb in paraffin-embedded human colon carcinoma tissue.

Anti-GRB4 / NCK2 Antibody (aa63-92) - LS-C164774 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NCK2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skin tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-GRB4 / NCK2 Antibody (aa119-276) IHC-plus™ - LS-B1286 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NCK2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1286 concentration 5 ug/ml.
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