NCK2

Gene Symbol	NCK2
Entrez Gene	8440
Alt Symbol	GRB4, NCKbeta
Species	Human
Gene Type	protein-coding
Description	NCK adaptor protein 2
Other Description	SH2/SH3 adaptor protein NCK-beta|cytoplasmic protein NCK2|growth factor receptor-bound protein 4|noncatalytic region of tyrosine kinase, beta
Swissprots	Q9BWN9 O43639 Q9UIC3 D3DVK1
Accessions	AAY14937 AAY24332 EAX01753 EAX01754 O43639 AF043119 AAC04831 AF047487 AAC80284 BC000103 AAH00103 BC007195 AAH07195 BC033176 BG480643 BM555604 BM920530 BU738133 CB959523 DB456958 XM_006712797 XP_006712860 XM_011511991 XP_011510293 XM_011511992 XP_011510294 NM_001004720 NP_001004720 NM_001004722 NP_001004722 NM_003581 NP_003572
Function	Adapter protein which associates with tyrosine- phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1- dependent transcriptional activation in response to activated Ras signaling. {ECO:0000269|PubMed:10026169, ECO:0000269|PubMed:16835242}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:16835242}. Endoplasmic reticulum {ECO:0000269|PubMed:16835242}.
Tissue Specificity	Ubiquitous.
Top Pathways	Axon guidance, T cell receptor signaling pathway, Pathogenic Escherichia coli infection, ErbB signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NCK2-Over-expression-Lysate - LY16288a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

NCK2 293T Cell Transient Overexpression Lysate(Denatured) - H00008440-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

NCK2 overexpression lysate - LY401190 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

NCK2 overexpression lysate - LY423904 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

NCK2 293 Cell Lysate - 401101 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

NCK2 293 Cell Lysate - 410001 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

NCK2 Overexpression Lysate (Denatured) - H00008440-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

NCK2 Overexpression Lysate (Native) - NBL1-13513 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

NCK2 Overexpression Lysate (Native) - NBL1-13512 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

NCK2 Over-expression Lysate Product - GWB-C42EEE from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

NCK2 Over-expression Lysate Product - GWB-7B4A32 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human NCK2 Knockdown Stable Cell Line - CSC-DC010185 from Creative biogene Category Cell Line Species Human

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