NCK2

Gene Symbol	NCK2
Entrez Gene	8440
Alt Symbol	GRB4, NCKbeta
Species	Human
Gene Type	protein-coding
Description	NCK adaptor protein 2
Other Description	SH2/SH3 adaptor protein NCK-beta|cytoplasmic protein NCK2|growth factor receptor-bound protein 4|noncatalytic region of tyrosine kinase, beta
Swissprots	Q9BWN9 O43639 Q9UIC3 D3DVK1
Accessions	AAY14937 AAY24332 EAX01753 EAX01754 O43639 AF043119 AAC04831 AF047487 AAC80284 BC000103 AAH00103 BC007195 AAH07195 BC033176 BG480643 BM555604 BM920530 BU738133 CB959523 DB456958 XM_006712797 XP_006712860 XM_011511991 XP_011510293 XM_011511992 XP_011510294 NM_001004720 NP_001004720 NM_001004722 NP_001004722 NM_003581 NP_003572
Function	Adapter protein which associates with tyrosine- phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1- dependent transcriptional activation in response to activated Ras signaling. {ECO:0000269|PubMed:10026169, ECO:0000269|PubMed:16835242}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:16835242}. Endoplasmic reticulum {ECO:0000269|PubMed:16835242}.
Tissue Specificity	Ubiquitous.
Top Pathways	Axon guidance, T cell receptor signaling pathway, Pathogenic Escherichia coli infection, ErbB signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Nck beta full length protein - ab132135 from Abcam Category Protein Source Wheat germ Species Human

Human Nck beta full length protein - ab167862 from Abcam Category Protein Source E. coli Species Human

GRB4 / NCK2 Antibody Blocking Peptide - LS-E2976 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCK2 Recombinant Protein - H00008440-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

NCK2 Partial Recombinant Protein - H00008440-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human NCK2 Protein - NBP2-23272 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

NCK2-Antibody-N-term-Blocking-peptide - BP14107a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Nck beta Protein - GTX108639-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

Human NCK2 protein - orb244397 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human NCK2 protein - orb191320 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Human NCK2 protein - orb80834 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Source E.coli

NCK2 protein (His tag) - 80R-2941 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

NCK2 (1-380, His-tag) - AR51059PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

NCK2 (1-380, His-tag) - AR51059PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

NCK2 - H00008440-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NCK2 - H00008440-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NCK2 - H00008440-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NCK2 - H00008440-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NCK2, 1-380aa, Human, His tag, E.coli - 01-P2235 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

NCK2 fusion protein - ag0262 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human NCK2 - BP000838-PKA-337 from Syd Labs Category Protein Prices $200.00, $295.00, $490.00 Sizes 2 µg, 5 µg, 10 µg Source E. coli-derived. Species Human

NCK2 Human - GWB-A4AFA2 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 25 μg, 1000 μg Species Human

Recombinant Human NCK Adaptor Protein 2 - NCK2-49H from Creative Biomart Category Protein Source Escherichia Coli.

Recombinant Human NCK2, His-tagged - NCK2-29113TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human NCK2, His-tagged - NCK2-15879H from Creative Biomart Category Protein Source E. coli Species Human

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