NR2F6

Gene Symbol	NR2F6
Entrez Gene	2063
Alt Symbol	EAR-2, EAR2, ERBAL2
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 2, group F, member 6
Other Description	ERBA-related gene-2\|V-erbA-related protein 2\|nuclear receptor V-erbA-related\|nuclear receptor subfamily 2 group F member 6\|v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2
Swissprots	Q9BUE8 Q6P586 Q5XGA0 B2RC68 P10588
Accessions	CAA31282 EAW84580 P10588 AB307712 BAH02303 AK298764 BAG60906 AK314961 BAG37465 BC002669 AAH02669 BC063018 AAH63018 BC084544 AAH84544 HQ692851 ADZ17362 NM_005234 NP_005225
Function	Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type- specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and
Subcellular Location	Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00407, ECO:0000269\|PubMed:10644740, ECO:0000269\|PubMed:18701084}.
Tissue Specificity	Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269\|PubMed:10713182}.

ARP-1 (B-2) - sc-271265 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

ARP-1 (B-2): sc-271265. Western blot analysis of ARP-1 expression in non-transfected: sc-117752 (A) and mouse ARP-1 transfected: sc-126444 (B) 293T whole cell lysates.

ARP-1 (D-12) - sc-271264 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

ARP-1 (D-12): sc-271264. Western blot analysis of ARP-1 expression in non-transfected: sc-117752 (A) and mouse ARP-1 transfected: sc-126444 (B) 293T whole cell lysates.

COUP-TF/EAR2 (F-11) - sc-166941 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

COUP-TF/EAR2 (F-11): sc-166941. Western blot analysis of EAR2 expression in non-transfected: sc-117752 (A) and mouse EAR2 transfected: sc-119899 (B) 293T whole cell lysates.

COUP-TF/EAR2 (H-230) - sc-30180 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

COUP-TF/EAR2 (H-230): sc-30180. Western blot analysis of COUP-TF/EAR2 expression in Ramos whole cell lysate.

EAR2 (L-12) - sc-23229 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Western blot analysis of EAR2 expression in rat liver tissue extract (A) and Hep G2 whole cell lysate (B). Antibodies tested include EAR2 (E-12): sc-23230 (A) and EAR2 (L-12): sc-23229 (B).

EAR2 (E-12) - sc-23230 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-NR2F6 antibody - ab65012 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

ab65012 at 1/500 - 1/1000 dilution staining NR2F6 in HepG2 cells by Immunofluorescence, in the absence or presence of the immunising peptide.

Anti-NR2F6 antibody - ab137496 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-NR2F6 antibody (ab137496) at 1/1000 dilutionLane 1 : HeLa whole cell lysateLane 2 : Raji whole cell lysateLysates/proteins at 30 µg per lane.

Anti-NR2F6 antibody - ab49240 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NR2F6 antibody (ab49240) at 5 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-NR2F6 antibody - ab49222 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NR2F6 antibody (ab49222) at 5 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-NR2F6 antibody - ab130363 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NR2F6 antibody (ab130363) at 1/100 dilution + MCF7 cell lysate at 35 µg

Anti-NR2F6 antibody [N2025] - ab41862 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	N2025

ab41858 staining NR2F6 in Rat gastric epithelial cells (10 ug/mL) by Immunohistochemistry, formalin-fixed paraffin embedded sections.

Anti-EAR2 / NR2F6 Antibody (N-Terminus) - LS-C30963 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa25-53, APC) - LS-C264732 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa25-53, AP) - LS-C264731 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa264-313) - LS-C30959 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa25-53, Biotin) - LS-C264733 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa21-70) - LS-C40527 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa25-53, FITC) - LS-C264734 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa25-53, Azide-free, HRP) - LS-C264735 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa25-53, PE) - LS-C264737 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa25-75) - LS-C288411 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa125-175) - LS-C288413 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa24-53) - LS-C323442 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-EAR2 / NR2F6 Antibody (aa25-53) - LS-C162994 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

NR2F6 Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The NR2F6 antibody detected the NR2F6 protein (arrow).

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