NR2F6

Gene Symbol	NR2F6
Entrez Gene	2063
Alt Symbol	EAR-2, EAR2, ERBAL2
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 2, group F, member 6
Other Description	ERBA-related gene-2|V-erbA-related protein 2|nuclear receptor V-erbA-related|nuclear receptor subfamily 2 group F member 6|v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2
Swissprots	Q9BUE8 Q6P586 Q5XGA0 B2RC68 P10588
Accessions	CAA31282 EAW84580 P10588 AB307712 BAH02303 AK298764 BAG60906 AK314961 BAG37465 BC002669 AAH02669 BC063018 AAH63018 BC084544 AAH84544 HQ692851 ADZ17362 NM_005234 NP_005225
Function	Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type- specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:10644740, ECO:0000269|PubMed:18701084}.
Tissue Specificity	Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10713182}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NR2F6 protein fragment - ab158381 from Abcam Category Protein Source Wheat germ Species Human

EAR2 / NR2F6 Antibody Blocking Peptide - LS-E4526 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EAR2 / NR2F6 Antibody Blocking Peptide - LS-E25429 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EAR2 / NR2F6 Antibody Blocking Peptide - LS-E29090 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

EAR2 / NR2F6 Antibody Blocking Peptide - LS-E29097 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

EAR2 / NR2F6 Antibody Blocking Peptide - LS-E11272 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human EAR2/NR2F6 Protein - H00002063-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NR2F6-Antibody-N-term-Blocking-Peptide - BP16861a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NR2F6 blocking peptide - GTX89874-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

NR2F6 Blocking Peptide - 33R-1199 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NR2F6 Blocking Peptide - abx062589 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Dog, Pig

NR2F6 Peptide - AC21-0257-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NR2F6 - H00002063-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NR2F6 - H00002063-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

EAR2 Peptide - 45-514P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

NR2F6 fusion protein - ag7614 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NR2F6 fusion protein - Ag7617 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

NR2F6 Blocking Peptide - CBP1395 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Dog, Pig

EAR2 (S40) Peptide - BS1925P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Nuclear receptor subfamily 2 group F member 6(NR2F6) - CSB-YP016058HU CSB-EP016058HU CSB-BP016058HU CSB-MP016058HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NR2F6 - TP301336 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

EAR2/NR2F6, Peptide - MBS426488 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

Recombinant Homo sapiens (Human) Nuclear receptor subfamily 2 group F member 6 - CSB-EP016058HU from Cusabio Category Protein Species Human

Recombinant Human Nuclear receptor subfamily 2 group F member 6 - CSB-MP016058HU from Cusabio Category Protein Source Mammalian cell Species Human

NR2F6 Peptide, Human - M34GP10599H from Creative Peptides Category Peptide Source Synthetic. Species Human

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