NR2F6

Gene Symbol	NR2F6
Entrez Gene	2063
Alt Symbol	EAR-2, EAR2, ERBAL2
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 2, group F, member 6
Other Description	ERBA-related gene-2|V-erbA-related protein 2|nuclear receptor V-erbA-related|nuclear receptor subfamily 2 group F member 6|v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2
Swissprots	Q9BUE8 Q6P586 Q5XGA0 B2RC68 P10588
Accessions	CAA31282 EAW84580 P10588 AB307712 BAH02303 AK298764 BAG60906 AK314961 BAG37465 BC002669 AAH02669 BC063018 AAH63018 BC084544 AAH84544 HQ692851 ADZ17362 NM_005234 NP_005225
Function	Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type- specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:10644740, ECO:0000269|PubMed:18701084}.
Tissue Specificity	Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10713182}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NR2F6 Gene cDNA Clone - orb144492 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human NR2F6 Gene ORF cDNA clone in cloning vector - HG13162-G from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13162-NY from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13162-NF from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, N-His tag - HG13162-NH from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13162-NM from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13162-CF from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13162-CM from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13162-ACR from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG13162-ANR from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, C-His tag - HG13162-CH from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid - HG13162-UT from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13162-ANG from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13162-ACG from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13162-G-F from Sino Biological Species Human

Human NR2F6 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13162-CY from Sino Biological Species Human

Human NR2F6 ORF clone (NM_005234.3) - CDCR058276 from Creative biogene Species Human

Human NR2F6 cDNA Clone(NM_005234.3) - CDFH012797 from Creative biogene Species Human

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