| Gene Symbol | MRGPRD |
|---|---|
| Entrez Gene | 116512 |
| Alt Symbol | MRGD, TGR7 |
| Species | Human |
| Gene Type | protein-coding |
| Description | MAS-related GPR, member D |
| Other Description | G-protein coupled receptor TGR7|beta-alanine receptor|mas-related G protein-coupled MRGD|mas-related G-protein coupled receptor member D |
| Swissprots | Q8TDS7 Q8NGK7 |
| Accessions | BAB89340 BAC06005 Q8TDS7 AB154410 BAD20638 AY427820 AAR05120 BC146427 AAI46428 BC156660 AAI56661 NM_198923 NP_944605 |
| Function | May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin- stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:15037633}; Multi-pass membrane protein {ECO:0000269|PubMed:15037633}. Note=Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine. |
MAS-related GPR, member D, ELISA Kit - MBS9340224 from MyBioSource
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Human MRGPRD ELISA Kit - E023673 from Biobool
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