MRGPRD

Gene Symbol	MRGPRD
Entrez Gene	116512
Alt Symbol	MRGD, TGR7
Species	Human
Gene Type	protein-coding
Description	MAS-related GPR, member D
Other Description	G-protein coupled receptor TGR7|beta-alanine receptor|mas-related G protein-coupled MRGD|mas-related G-protein coupled receptor member D
Swissprots	Q8TDS7 Q8NGK7
Accessions	BAB89340 BAC06005 Q8TDS7 AB154410 BAD20638 AY427820 AAR05120 BC146427 AAI46428 BC156660 AAI56661 NM_198923 NP_944605
Function	May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin- stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
Subcellular Location	Cell membrane {ECO:0000269|PubMed:15037633}; Multi-pass membrane protein {ECO:0000269|PubMed:15037633}. Note=Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GPCR TGR7 full length protein - ab165111 from Abcam Category Protein Source Wheat germ Species Human

MRGD / MRGPRD Antibody Blocking Peptide - LS-E28891 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

MRGD / MRGPRD Antibody Blocking Peptide - LS-E28892 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

MRGD / MRGPRD Antibody Blocking Peptide - LS-E28893 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human MRGPRD Protein - H00116512-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

MRGD / TGR7 - H00116512-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

MRGPRD fusion protein - ag20333 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

MRGPRD fusion protein - ag20316 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ChemiSCREEN™ Human Recombinant MrgD Mas-Related Receptor Calcium-Optimized Stable Cell Line - HTS206C from EMD Millipore Species Human

ChemiSCREEN™ Membrane Preparation Recombinant Human MrgD Mas-Related Gene Family Receptor - HTS206M from EMD Millipore Prices $596.00 Sizes 200 units Species Human

MRGPRD Recombinant Protein Antigen - NBP1-91964PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MRGPRD Peptide, Human - M34GP09707H from Creative Peptides Category Peptide Source Synthetic. Species Human

Mas-related G-protein coupled receptor member D (MRGPRD), Recombinant Protein - MBS7020731 from MyBioSource Category Protein Prices $1,130.00, $2,115.00, $3,325.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

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