NKIRAS1

Gene Symbol	NKIRAS1
Entrez Gene	28512
Alt Symbol	KBRAS1, kappaB-Ras1
Species	Human
Gene Type	protein-coding
Description	NFKB inhibitor interacting Ras-like 1
Other Description	I-kappa-B-interacting Ras-like protein 1|NF-kappa-B inhibitor-interacting Ras-like protein 1|NFKB inhibitor interacting Ras-like protein 1|kappa B-Ras protein 1|kappa B-ras 1
Swissprots	Q96K18 Q9NYS0
Accessions	ABC40740 CAD34857 EAW64335 EAW64336 Q9NYS0 AF229839 AAF34998 AK027749 BAB55341 BC012145 AAH12145 BC066940 AAH66940 BG713995 EU176465 ABW03916 XM_005265076 XP_005265133 XM_005265077 XP_005265134 XM_005265078 XP_005265135 NM_020345 NP_065078
Function	Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. {ECO:0000269|PubMed:10657303, ECO:0000269|PubMed:12672800, ECO:0000269|PubMed:15024091}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15024091}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:10657303}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NKIRAS1 overexpression lysate - LY412541 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

NKIRAS1 293 Cell Lysate - 406146 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

NKIRAS1 Overexpression Lysate (Native) - NBL1-13655 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

NKIRAS1 Over-expression Lysate Product - GWB-15CAC4 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human NKIRAS1 Knockdown Stable Cell Line - CSC-DC010403 from Creative biogene Category Cell Line Species Human

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