NKIRAS1

Gene Symbol	NKIRAS1
Entrez Gene	28512
Alt Symbol	KBRAS1, kappaB-Ras1
Species	Human
Gene Type	protein-coding
Description	NFKB inhibitor interacting Ras-like 1
Other Description	I-kappa-B-interacting Ras-like protein 1|NF-kappa-B inhibitor-interacting Ras-like protein 1|NFKB inhibitor interacting Ras-like protein 1|kappa B-Ras protein 1|kappa B-ras 1
Swissprots	Q96K18 Q9NYS0
Accessions	ABC40740 CAD34857 EAW64335 EAW64336 Q9NYS0 AF229839 AAF34998 AK027749 BAB55341 BC012145 AAH12145 BC066940 AAH66940 BG713995 EU176465 ABW03916 XM_005265076 XP_005265133 XM_005265077 XP_005265134 XM_005265078 XP_005265135 NM_020345 NP_065078
Function	Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. {ECO:0000269|PubMed:10657303, ECO:0000269|PubMed:12672800, ECO:0000269|PubMed:15024091}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15024091}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:10657303}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

κB-Ras1 siRNA (h) - sc-41796 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

κB-Ras1 shRNA Plasmid (h) - sc-41796-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

κB-Ras1 shRNA (h) Lentiviral Particles - sc-41796-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NKIRAS1 RNAi - H00028512-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU015361 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15323 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15323 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08270 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr08270

NKIRAS1 siRNA (Human) - CRH9118 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human NKIRAS1 (NM_020345.3) - SHH352728 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human NKIRAS1(NM_020345.3) - SHR008088 from Creative biogene Category siRNA Species Reactivities Human

Human NKIRAS1 siRNA - orb269620 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

NKIRAS1 shRNA Plasmid (Human) - CHH9118 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

NKIRAS1 miRNA 3'UTR clone - MiUTR1H-06777 from Creative biogene Species Reactivities Human

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