IPO11

Gene Symbol	IPO11
Entrez Gene	51194
Alt Symbol	RanBP11
Species	Human
Gene Type	protein-coding
Description	importin 11
Other Description	Ran binding protein 11|imp11|importin-11|ran-binding protein 11
Swissprots	Q9NSJ6 Q9UI26 Q8N5R2 A6NGJ5 B4DZ73 Q9NVB1 D3DW98
Accessions	EAW51379 EAW51380 EAW51381 Q9UI26 AF111109 AAF21936 AK001696 BAA91843 AK023177 BAG51165 AK124969 AK302781 BAG63985 AL162083 CAB82416 AL705962 BC031694 AAH31694 BC033776 AAH33776 BC043163 BM966917 DA473424 DQ894533 ABM85459 EU176274 ABW03725 NM_001134779 NP_001128251 NM_016338 NP_057422
Function	Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBE2E3, and of RPL12 (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:11032817}. Nucleus {ECO:0000269|PubMed:11032817}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IPO11 protein fragment - ab127131 from Abcam Category Protein Source E. coli Species Human

IPO11 / Importin 11 Antibody Blocking Peptide - LS-E9770 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IPO11 / Importin 11 Antibody Blocking Peptide - LS-E10250 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IPO11-Antibody-N-term-Blocking-Peptide - BP8772a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IPO11-Antibody-C-term-Blocking-Peptide - BP9661b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IPO11 fusion protein - ag4231 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

IPO11 fusion protein - ag5659 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Importin-11(IPO11) ,partial - CSB-YP887057HU CSB-EP887057HU CSB-BP887057HU CSB-MP887057HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RanBP11 / Importin-11 (transcript variant 2) - TP307519 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Importin 11 Recombinant Protein Antigen - NBP2-49505PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

IPO11 Peptide, Human - M34GP07701H from Creative Peptides Category Peptide Source Synthetic. Species Human

Importin-11 (IPO11), partial, Recombinant Protein - MBS1487124 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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