IPO11

Gene Symbol IPO11
Entrez Gene 51194
Alt Symbol RanBP11
Species Human
Gene Type protein-coding
Description importin 11
Other Description Ran binding protein 11|imp11|importin-11|ran-binding protein 11
Swissprots Q9NSJ6 Q9UI26 Q8N5R2 A6NGJ5 B4DZ73 Q9NVB1 D3DW98
Accessions EAW51379 EAW51380 EAW51381 Q9UI26 AF111109 AAF21936 AK001696 BAA91843 AK023177 BAG51165 AK124969 AK302781 BAG63985 AL162083 CAB82416 AL705962 BC031694 AAH31694 BC033776 AAH33776 BC043163 BM966917 DA473424 DQ894533 ABM85459 EU176274 ABW03725 NM_001134779 NP_001128251 NM_016338 NP_057422
Function Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBE2E3, and of RPL12 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11032817}. Nucleus {ECO:0000269|PubMed:11032817}.

Importin-11 CRISPR/Cas9 KO Plasmid (h) - sc-406500 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Importin-11 HDR Plasmid (h) - sc-406500-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Importin-11 Double Nickase Plasmid (h) - sc-406500-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Importin-11 Double Nickase Plasmid (h2) - sc-406500-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Importin-11 CRISPR Activation Plasmid (h) - sc-406500-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Importin-11 CRISPR Activation Plasmid (h2) - sc-406500-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Importin-11 Lentiviral Activation Particles (h) - sc-406500-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Importin-11 Lentiviral Activation Particles (h2) - sc-406500-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Importin-11 siRNA (h) - sc-91819 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Importin-11 shRNA Plasmid (h) - sc-91819-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Importin-11 shRNA (h) Lentiviral Particles - sc-91819-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Importin 11 RNAi - H00051194-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU130721 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10729 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10729 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08662 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08662

IPO11 siRNA (Human) - CRH9597 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IPO11 - MBS8212794 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IPO11 (NM_016338.4) - SHH320141 from Creative biogene

Category siRNA
Species Reactivities Human

Human IPO11 siRNA - orb270099 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IPO11 shRNA Plasmid (Human) - CHH9597 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IPO11 miRNA 3'UTR clone - MiUTR3H-11534 from Creative biogene

Species Reactivities Human

IPO11 miRNA 3'UTR clone - MiUTR3H-11535 from Creative biogene

Species Reactivities Human
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