MCM6

Gene Symbol MCM6
Entrez Gene 4175
Alt Symbol MCG40308, Mis5, P105MCM
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex component 6
Other Description DNA replication licensing factor MCM6|MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe)|minichromosome maintenance deficient (mis5, S. pombe) 6
Swissprots B2R6H2 Q99859 Q13504 Q14566
Accessions AAO26043 AAX88925 AAY15028 CAN37618 CDH61697 EAX11621 Q14566 AA577398 AK299236 BAG61268 AK303455 BAG64499 AK312575 BAG35469 AU124893 BC008774 BC020268 BC032374 AAH32374 CN389677 D84557 BAA12699 DA521248 U46838 AAC50766 NM_005915 NP_005906
Function Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. {ECO:0000269|PubMed:9305914}.
Subcellular Location Nucleus. Note=Binds to chromatin during G1 and detach from it during S phase.
Top Pathways DNA replication, Cell cycle

Rabbit anti-MCM6 Antibody, Affinity Purified - PLA0063 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunohistochemistry</B><BR/>Rabbit Anti-MCM6 Antibody, Affinity Purified: <B>Cat. No. PLA0063</B>: Detection of Human and Mouse MCM6 by Immunohistochemistry. Sample: FFPE section of Human breast carcinoma (left) and Mouse squamous cell carcinoma (right). Antibody: Affinity purified Rabbit Anti-MCM6 (<B>Cat. No. PLA0063</B>) used at a dilution of 1:1,000 (1 μg/mL). Detection: DAB

Goat anti-MCM6 Antibody, Affinity Purified - PLA0041 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunohistochemistry</B><BR/>Goat Anti-MCM6 Antibody, Affinity Purified: <B>Cat. No. PLA0041</B>: Detection of Human MCM6 by Immunohistochemistry. Sample: FFPE section of Human ovarian carcinoma. Antibody: Affinity purified goat Anti-MCM6 (<B>Cat. No. PLA0041</B>) used at a dilution of 1:1,000 (1 μg/mL). Detection: DAB

minichromosome maintenance complex component 6, ELISA Kit - MBS909031 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 11.72 pg/ml
Range 46.88 pg/ml-3000 pg/ml

Human DNA replication licensing factor MCM6(MCM6) ELISA kit - CSB-EL013596HU from Cusabio

Category ELISA Kit
Sensitivity 11.72 pg/ml
Range 46.88 pg/ml-3000 pg/ml

Human DNA replication licensing factor MCM6 (MCM6) ELISA Kit - EKC33486 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 11.72 pg/ml
Range 46.88 pg/ml-3000 pg/ml

Human MCM6 ELISA Kit - E024575 from Biobool

Category ELISA Kit
Sensitivity 11.72 pg/ml

MCM6 ELISA Kit (Human) (OKCA01206) - OKCA01206 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 11.72 pg/mL
Range 46.88 - 3,000 pg/mL

MCM6 (minichromosome maintenance complex component 6), ELISA Kit - MBS7606602 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 28.125pg/ml
Range 46.88-3000pg/ml

DNA replication licensing factor MCM6, ELISA Kit - MBS285904 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human MCM6 ELISA Kit (Sandwich ELISA) - LS-F31923 from LifeSpan Bioscience

Category ELISA Kit
Sensitivity 28.125
Range 46.88-3000 pg/ml
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