MCM6

Gene Symbol	MCM6
Entrez Gene	4175
Alt Symbol	MCG40308, Mis5, P105MCM
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex component 6
Other Description	DNA replication licensing factor MCM6|MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe)|minichromosome maintenance deficient (mis5, S. pombe) 6
Swissprots	B2R6H2 Q99859 Q13504 Q14566
Accessions	AAO26043 AAX88925 AAY15028 CAN37618 CDH61697 EAX11621 Q14566 AA577398 AK299236 BAG61268 AK303455 BAG64499 AK312575 BAG35469 AU124893 BC008774 BC020268 BC032374 AAH32374 CN389677 D84557 BAA12699 DA521248 U46838 AAC50766 NM_005915 NP_005906
Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. {ECO:0000269|PubMed:9305914}.
Subcellular Location	Nucleus. Note=Binds to chromatin during G1 and detach from it during S phase.
Top Pathways	DNA replication, Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MCM6 full length protein - ab114758 from Abcam Category Protein Source Wheat germ Species Human

Human MCM6 protein fragment - ab152517 from Abcam Category Protein Source Wheat germ Species Human

MCM6 Antibody Blocking Peptide - LS-E3545 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM6 Antibody Blocking Peptide - LS-E13142 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MCM6 Protein - H00004175-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MCM6 Protein - H00004175-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MCM6-Antibody-N-term-Blocking-Peptide - BP14743a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MCM6 Blocking Peptide - 33R-7967 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM6 - H00004175-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MCM6 - H00004175-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MCM6 - H00004175-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MCM6 - H00004175-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MCM6 fusion protein - Ag4180 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

MCM6 fusion protein - Ag4354 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human MCM6 - MCM6-28042TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human DNA replication licensing factor MCM6(MCM6) ,partial - CSB-YP618894HU CSB-EP618894HU CSB-BP618894HU CSB-MP618894HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MCM6 - TP307097 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MCM6 Blocking Peptide (OESA09460) - OESA09460 from Aviva Systems Biology Category Peptide Prices $245.00 Sizes 50 µg Species Human

MCM6 Recombinant Protein Antigen - NBP1-82642PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

MCM6 Peptide, Human - M34GP09318H from Creative Peptides Category Peptide Source Synthetic. Species Human

DNA replication licensing factor MCM6 (MCM6), partial, Recombinant Protein - MBS1328866 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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