MCM6

Gene Symbol	MCM6
Entrez Gene	4175
Alt Symbol	MCG40308, Mis5, P105MCM
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex component 6
Other Description	DNA replication licensing factor MCM6|MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe)|minichromosome maintenance deficient (mis5, S. pombe) 6
Swissprots	B2R6H2 Q99859 Q13504 Q14566
Accessions	AAO26043 AAX88925 AAY15028 CAN37618 CDH61697 EAX11621 Q14566 AA577398 AK299236 BAG61268 AK303455 BAG64499 AK312575 BAG35469 AU124893 BC008774 BC020268 BC032374 AAH32374 CN389677 D84557 BAA12699 DA521248 U46838 AAC50766 NM_005915 NP_005906
Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. {ECO:0000269|PubMed:9305914}.
Subcellular Location	Nucleus. Note=Binds to chromatin during G1 and detach from it during S phase.
Top Pathways	DNA replication, Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MCM6 - MBS1270883 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC032374

Human MCM6 ORF Clone(NM_005915.5) - CDCL169785 from Creative Biomart Species Human Accession NM_005915.5

Human MCM6 Gene ORF cDNA clone in cloning vector - HG14317-G from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid - HG14317-UT from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14317-CY from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14317-ACR from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14317-ANR from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14317-NF from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14317-NM from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14317-CF from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14317-CM from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, N-His tag - HG14317-NH from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14317-ANG from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14317-ACG from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14317-NY from Sino Biological Species Human

Human MCM6 Gene ORF cDNA clone expression plasmid, C-His tag - HG14317-CH from Sino Biological Species Human

Human MCM6 ORF Clone (BC032374) - CDCS412481 from Creative biogene Species Human Accession Q14566

Human MCM6 ORF clone (BC032374) - CDCB159186 from Creative biogene Species Human

Human MCM6 Gene cDNA Clone - orb144204 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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