NCKAP1

Gene Symbol NCKAP1
Entrez Gene 10787
Alt Symbol HEM2, NAP1, NAP125, p125Nap1
Species Human
Gene Type protein-coding
Description NCK-associated protein 1
Other Description membrane-associated protein HEM-2|nck-associated protein 1
Swissprots Q53Y35 Q53QN5 Q9Y2A7 Q53S94 O60329
Accessions AAX93118 AAY24196 EAX10952 EAX10953 EAX10954 EAX10955 EAX10956 EAX10957 Q9Y2A7 AB011159 BAA25513 AB014509 BAA77295 AI215133 AK001291 BAG50887 AK002153 BAG51019 AK292914 BAF85603 BC015025 AAH15025 BT007033 AAP35681 CA314471 DQ893545 ABM84471 DQ893809 ABM84735 XM_006712200 XP_006712263 XM_006712201 XP_006712264 NM_013436 NP_038464 NM_205842 NP_995314
Function Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell projection, lamellipodium membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=At the interface between the lamellipodial actin meshwork and the membrane. {ECO:0000250}.
Tissue Specificity Expressed in all tissues examined except peripheral blood leukocytes, with highest expression in brain, heart, and skeletal muscle.
Top Pathways Regulation of actin cytoskeleton

NAP125 (N-12) - sc-161124 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NAP125 (N-12): sc-161124. Western blot analysis of NAP125 expression in C2C12 whole cell lysate.

Anti-NCKAP1 antibody - ab126061 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-NCKAP1 antibody (ab126061) at 1/1000 dilution + U-87 MG whole cell lysate at 30 µg

Anti-NCKAP1 antibody - ab198924 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling NCKAP1 with ab198924 at 1/30 dilution.

Anti-NCKAP1 antibody - ab96715 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-NCKAP1 antibody (ab96715) at 1/500 dilution + HepG2 whole cell lysate at 30 µg

Anti-NCKAP1 antibody - ab140856 from Abcam

Prices $242.00
Sizes 200 µl
Host Goat
Clonality Polyclonal

Anti-NCKAP1 antibody - Aminoterminal end - ab69867 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NCKAP1 / NAP125 Antibody (aa703-715) - LS-C155062 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-NCKAP1 / NAP125 Antibody (aa631-659, AP) - LS-C264093 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NCKAP1 / NAP125 Antibody (aa631-659, APC) - LS-C264095 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NCKAP1 / NAP125 Antibody (aa631-659, Biotin) - LS-C264096 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NCKAP1 / NAP125 Antibody (aa631-659, FITC) - LS-C264097 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NCKAP1 / NAP125 Antibody (aa631-659, Azide-free, HRP) - LS-C264098 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NCKAP1 / NAP125 Antibody (aa631-659, PE) - LS-C264099 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NCKAP1 / NAP125 Antibody (aa640-670) - LS-C323250 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NCKAP1 / NAP125 Antibody (aa631-659) - LS-C164775 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NCKAP1 Antibody western blot of A2058 cell line lysates (35 ug/lane). The NCKAP1 antibody detected the NCKAP1 protein (arrow).

Anti-NCKAP1 / NAP125 Antibody (aa693-936) - LS-C185724 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (50 ug of whole cell lysate). A: Mouse brain. 5% SDS PAGE. NCKAP1 / NAP125 antibody diluted at 1:1000.

Anti-NCKAP1 / NAP125 Antibody (N-Terminus) - LS-C155424 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Lung Papillary Adenocarcinoma, using NCKAP1 antibody at 1:250 dilution.

NCKAP1 Antibody - NBP1-83269 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NCKAP1 Antibody [NBP1-83269] - Analysis in control (vector only transfected HEK293T lysate) and nCKAP1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

NCKAP1 Antibody - NBP2-19491 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NCKAP1 Antibody [NBP2-19491] - Sample (30 ug of whole cell lysate) A: U87-MG 5% SDS PAGE gel, diluted at 1:1000.

NCKAP1 Antibody - NBP1-32339 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NCKAP1 Antibody [NBP1-32339] - Internal detects NCKAP1 protein by Western blot analysis. A. 50 ug rat brain lysate/extract 5 % SDS-PAGE, dilution: 1:1000

NAP1 Antibody - NBP1-81262 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: NAP1 Antibody [NBP1-81262] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

NCKAP1 Antibody - NBP2-26086 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

NCKAP1 Polyclonal Antibody - bs-6204R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NCKAP1 antibody produced in rabbit - HPA020449 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NCKAP1: <B>Cat. No. HPA020449</B>: Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells.

Anti-NCKAP1 (N-terminal) antibody produced in rabbit - SAB2701228 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NCKAP1 (N-terminal): <B>Cat. No. SAB2701228</B>: Immunohistochemical analysis of paraffin-embedded Lung Papillary Adenocarcinoma, using NCKAP1 antibody at 1:500 dilution.
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