NCKAP1

Gene Symbol NCKAP1
Entrez Gene 10787
Alt Symbol HEM2, NAP1, NAP125, p125Nap1
Species Human
Gene Type protein-coding
Description NCK-associated protein 1
Other Description membrane-associated protein HEM-2|nck-associated protein 1
Swissprots Q53Y35 Q53QN5 Q9Y2A7 Q53S94 O60329
Accessions AAX93118 AAY24196 EAX10952 EAX10953 EAX10954 EAX10955 EAX10956 EAX10957 Q9Y2A7 AB011159 BAA25513 AB014509 BAA77295 AI215133 AK001291 BAG50887 AK002153 BAG51019 AK292914 BAF85603 BC015025 AAH15025 BT007033 AAP35681 CA314471 DQ893545 ABM84471 DQ893809 ABM84735 XM_006712200 XP_006712263 XM_006712201 XP_006712264 NM_013436 NP_038464 NM_205842 NP_995314
Function Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell projection, lamellipodium membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=At the interface between the lamellipodial actin meshwork and the membrane. {ECO:0000250}.
Tissue Specificity Expressed in all tissues examined except peripheral blood leukocytes, with highest expression in brain, heart, and skeletal muscle.
Top Pathways Regulation of actin cytoskeleton

NCKAP1 293T Cell Transient Overexpression Lysate(Denatured) - H00010787-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

NCKAP1 overexpression lysate - LY415547 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

NCKAP1 293 Cell Lysate - 407328 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

NCKAP1 Overexpression Lysate (Native) - NBP2-07394 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: NCKAP1 Overexpression Lysate (Adult Normal) [NBP2-07394] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NCKAP1.

NCKAP1 Over-expression Lysate Product - GWB-50DAED from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

NCKAP1 Overexpression Lysate (Denatured) - H00010787-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human NCKAP1 Knockdown Stable Cell Line - CSC-DC010186 from Creative biogene

Category Cell Line
Species Human
Search more