NCKAP1

Gene Symbol	NCKAP1
Entrez Gene	10787
Alt Symbol	HEM2, NAP1, NAP125, p125Nap1
Species	Human
Gene Type	protein-coding
Description	NCK-associated protein 1
Other Description	membrane-associated protein HEM-2|nck-associated protein 1
Swissprots	Q53Y35 Q53QN5 Q9Y2A7 Q53S94 O60329
Accessions	AAX93118 AAY24196 EAX10952 EAX10953 EAX10954 EAX10955 EAX10956 EAX10957 Q9Y2A7 AB011159 BAA25513 AB014509 BAA77295 AI215133 AK001291 BAG50887 AK002153 BAG51019 AK292914 BAF85603 BC015025 AAH15025 BT007033 AAP35681 CA314471 DQ893545 ABM84471 DQ893809 ABM84735 XM_006712200 XP_006712263 XM_006712201 XP_006712264 NM_013436 NP_038464 NM_205842 NP_995314
Function	Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell projection, lamellipodium membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=At the interface between the lamellipodial actin meshwork and the membrane. {ECO:0000250}.
Tissue Specificity	Expressed in all tissues examined except peripheral blood leukocytes, with highest expression in brain, heart, and skeletal muscle.
Top Pathways	Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NCKAP1 protein fragment - ab153130 from Abcam Category Protein Source Wheat germ Species Human

NAP1 / TAB3 Antibody Blocking Peptide - LS-E4703 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NAP1 / TAB3 Antibody Blocking Peptide - LS-E30091 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NAP1 / TAB3 Antibody Blocking Peptide - LS-E26487 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NAP1 / TAB3 Antibody Blocking Peptide - LS-E26496 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCKAP1 / NAP125 Antibody Blocking Peptide - LS-E8043 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCKAP1 / NAP125 Antibody Blocking Peptide - LS-E27965 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NCKAP1 Protein - H00010787-P01 from Novus Biologicals Category Protein Prices $305.00, $445.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human NCKAP1 Protein - H00010787-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NCKAP1-Antibody-Center-Blocking-peptide - BP5916c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAP3K7IP3 (aa 274 to 285) blocking peptide - GTX88964-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

MAP3K7IP3 (aa 59 to 69) blocking peptide - GTX88918-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

NAP1L1 protein (His tag) - 80R-2040 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

NAP1 Blocking Peptide - abx063949 from Abbexa Category Peptide Species Human, Monkey

NCKAP1 Peptide - AC21-2730-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NAP1 - H00010787-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NAP1 - H00010787-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NAP1 - H00010787-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NAP1 - H00010787-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NCKAP1 Peptide - 43-096P from ProSci Category Peptide

NAP1;NCKAP1 fusion protein - Ag2788 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

NAP1;NCKAP1 fusion protein - ag18499 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human NCKAP1, GST-tagged - NCKAP1-1176H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Nucleosome Assembly Protein 1 Like Protein 1 (NAP1L1) - RPH571Hu01 from Cloud-clone Category Protein Source E.coli Species Human

NCKAP1, Peptide - MBS427920 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

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