Gene Symbol | CD320 |
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Entrez Gene | 51293 |
Alt Symbol | 8D6, 8D6A, TCBLR |
Species | Human |
Gene Type | protein-coding |
Description | CD320 molecule |
Other Description | 8D6 antigen|CD320 antigen|FDC-SM-8D6|FDC-signaling molecule 8D6|transcobalamin receptor |
Swissprots | B2RDS5 Q9NPF0 F5H6D3 Q53HF7 D6W668 |
Accessions | EAW68936 EAW68939 Q9NPF0 AF161254 AAF61850 AK058014 AK222623 BAD96343 AK315656 BAG38022 AL136652 CAB66587 AL365453 CAB97009 AL365455 CAB97010 AY358420 AAQ88786 BC000668 AAH00668 BC007083 AAH07083 BC036814 CB141050 CR457174 CAG33455 EU831651 ACE87251 NM_001165895 NP_001159367 NM_016579 NP_057663 |
Function | Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin. {ECO:0000269|PubMed:11418631, ECO:0000269|PubMed:18779389}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed abundantly on follicular dendritic cells (FDCs). {ECO:0000269|PubMed:10727470}. |
8D6 (F-12) - sc-393892 from Santa Cruz Biotechnology
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8D6 (S-16) - sc-54155 from Santa Cruz Biotechnology
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Anti-CD320 antibody - ab121433 from Abcam
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Anti-CD320 antibody - C-terminal - ab171634 from Abcam
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Anti-CD320 Antibody (Extracellular Domain) - LS-C125332 from LifeSpan Bioscience
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Anti-CD320 Antibody (Extracellular Domain, Biotin) - LS-C125333 from LifeSpan Bioscience
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Anti-CD320 Antibody (aa153-182, AP) - LS-C253969 from LifeSpan Bioscience
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Anti-CD320 Antibody (aa153-182, Biotin) - LS-C253971 from LifeSpan Bioscience
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Anti-CD320 Antibody (aa153-182, FITC) - LS-C253973 from LifeSpan Bioscience
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Anti-CD320 Antibody (aa153-182, APC) - LS-C253970 from LifeSpan Bioscience
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Anti-CD320 Antibody (aa153-182, Azide-free, HRP) - LS-C253977 from LifeSpan Bioscience
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Anti-CD320 Antibody (aa152-182) - LS-C320171 from LifeSpan Bioscience
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Anti-CD320 Antibody (aa153-182, PE) - LS-C253978 from LifeSpan Bioscience
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Anti-CD320 Antibody (aa153-182) - LS-C159308 from LifeSpan Bioscience
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Anti-CD320 Antibody (aa36-256) - LS-C314672 from LifeSpan Bioscience
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CD320/TCblR/8D6A Antibody - AF1557 from Novus Biologicals
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CD320/TCblR/8D6A Antibody - NBP1-89348 from Novus Biologicals
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CD320/TCblR/8D6A Antibody (4F2) - H00051293-M04A from Novus Biologicals
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CD320/TCblR/8D6A Antibody - H00051293-A01 from Novus Biologicals
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CD320/TCblR/8D6A Antibody [Biotin] - BAF1557 from Novus Biologicals
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ANTI-CD320 (C-TERM) antibody produced in rabbit - SAB1304603 from Sigma-Aldrich
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Monoclonal Anti-CD320 antibody produced in mouse - SAB1409408 from Sigma-Aldrich
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Anti-CD320 antibody produced in rabbit - HPA014500 from Sigma-Aldrich
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CD320-Antibody-C-term - AP13137b from Abgent, a WuXi AppTec company
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CD320 Antibody - C-terminal region (OAAB09435) - OAAB09435 from Aviva Systems Biology
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