Gene Symbol | CD320 |
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Entrez Gene | 51293 |
Alt Symbol | 8D6, 8D6A, TCBLR |
Species | Human |
Gene Type | protein-coding |
Description | CD320 molecule |
Other Description | 8D6 antigen|CD320 antigen|FDC-SM-8D6|FDC-signaling molecule 8D6|transcobalamin receptor |
Swissprots | B2RDS5 Q9NPF0 F5H6D3 Q53HF7 D6W668 |
Accessions | EAW68936 EAW68939 Q9NPF0 AF161254 AAF61850 AK058014 AK222623 BAD96343 AK315656 BAG38022 AL136652 CAB66587 AL365453 CAB97009 AL365455 CAB97010 AY358420 AAQ88786 BC000668 AAH00668 BC007083 AAH07083 BC036814 CB141050 CR457174 CAG33455 EU831651 ACE87251 NM_001165895 NP_001159367 NM_016579 NP_057663 |
Function | Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin. {ECO:0000269|PubMed:11418631, ECO:0000269|PubMed:18779389}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed abundantly on follicular dendritic cells (FDCs). {ECO:0000269|PubMed:10727470}. |
Human CD320 full length protein - ab162495 from Abcam
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Human CD320 protein fragment - ab162496 from Abcam
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Human CD320 protein fragment - ab185405 from Abcam
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CD320 Antibody Blocking Peptide - LS-E2214 from LifeSpan Bioscience
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Recombinant Human CD320/TCblR/8D6A Protein - H00051293-Q01 from Novus Biologicals
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CD320/TCblR/8D6A Recombinant Protein - H00051293-P01 from Novus Biologicals
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Recombinant Human CD320/TCblR/8D6A Protein - H00051293-G01 from Novus Biologicals
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CD320-Antibody-C-term-Blocking-Peptide - BP13137b from Abgent, a WuXi AppTec company
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Recombinant Human CD320/TCblR/8D6A Fc Chimera, CF - 1557-CD-050 from R&D Systems
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Recombinant human CD320 antigen (OPCA00877) - OPCA00877 from Aviva Systems Biology
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Human CD320 protein - orb180217 from Biorbyt
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Human CD320 protein - orb245467 from Biorbyt
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Human 8D6A protein - orb180216 from Biorbyt
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CD320 / 8D6A - H00051293-G01 from Acris Antibodies
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CD320 / 8D6A - H00051293-Q01-10 from Acris Antibodies
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CD320 / 8D6A - H00051293-Q01-25 from Acris Antibodies
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CD320 / 8D6 antigen - H00051293-P01-02 from Acris Antibodies
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CD320 fusion protein - ag0344 from Proteintech Group
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CD320 fusion protein - ag17605 from Proteintech Group
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Recombinant Cluster Of Differentiation 320 (CD320) - RPB007Ra01 from Uscn Life Science Inc.
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Chromogranin A / Vasostatin 2 - ABP-84-0150 from Nordic BioSite
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Chromogranin A / Vasostatin 2 - ABP-84-0110 from Nordic BioSite
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Chromogranin A / Vasostatin 2 - ABP-84-01100 from Nordic BioSite
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Chromogranin A / Vasostatin 2 - ABP-84-011000 from Nordic BioSite
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Chromogranin A / Vasostatin 2 - ABP-84-0120 from Nordic BioSite
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