Gene Symbol | PCBD1 |
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Entrez Gene | 5092 |
Alt Symbol | DCOH, PCBD, PCD, PHS |
Species | Human |
Gene Type | protein-coding |
Description | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
Other Description | 4-alpha-hydroxy-tetrahydropterin dehydratase|6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)|dimerizing cofactor for HNF1|phenylalanine hydroxylase-stimulating protein|pterin-4-alpha-carbinolamine dehydratase |
Swissprots | P61457 |
Accessions | AAA35670 AAA35671 AAA35672 AAA69662 EAW54416 EAW54417 P61457 AA397961 AA736613 AF082858 AAD25732 BC006324 AAH06324 BI548743 BM724638 BQ685076 BQ897536 CR542194 CAG46991 L41559 AAA69663 M83742 XM_005269877 XP_005269934 NM_000281 NP_000272 NM_001289797 NP_001276726 |
Function | Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. |
Subcellular Location | Cytoplasm. Nucleus. Note=Cytoplasmic and/or nuclear. |
PCBD1 (N-12) - sc-165196 from Santa Cruz Biotechnology
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PCBD1 (K-13) - sc-165195 from Santa Cruz Biotechnology
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PCBD1 (CD-37) - sc-100488 from Santa Cruz Biotechnology
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Anti-PCBD1 antibody - ab55503 from Abcam
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Anti-PCBD1 antibody [EPR9760(B)] - ab138518 from Abcam
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Anti-PCBD1 / PHS Antibody (aa11-37, AP) - LS-C265733 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (aa11-37, APC) - LS-C265735 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (aa11-37, Biotin) - LS-C265736 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (aa11-37, FITC) - LS-C265737 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (aa11-37, Azide-free, HRP) - LS-C265738 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (clone 1G11-H5) - LS-C197849 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (aa11-37, PE) - LS-C265739 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (C-Terminus) - LS-C145430 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (N-Terminus) - LS-C101670 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (aa27-56) - LS-C323822 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (aa1-105, Azide-free) - LS-C328408 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (N-Terminus) - LS-C101393 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody - LS-C334681 from LifeSpan Bioscience
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Anti-PCBD1 / PHS Antibody (aa11-37) - LS-C163406 from LifeSpan Bioscience
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PCBD1 Antibody - NBP1-84297 from Novus Biologicals
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PCBD1 Antibody (1G11-H5) - H00005092-M01 from Novus Biologicals
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PCBD1 Antibody - H00005092-A01 from Novus Biologicals
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Anti-PCBD1 antibody produced in rabbit - HPA037575 from Sigma-Aldrich
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Anti-PCBD1 (ab1) antibody produced in rabbit - SAB2101735 from Sigma-Aldrich
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Anti-PCBD1 (56-70) antibody produced in rabbit - SAB1100465 from Sigma-Aldrich
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