Gene Symbol | PCBD1 |
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Entrez Gene | 5092 |
Alt Symbol | DCOH, PCBD, PCD, PHS |
Species | Human |
Gene Type | protein-coding |
Description | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
Other Description | 4-alpha-hydroxy-tetrahydropterin dehydratase|6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)|dimerizing cofactor for HNF1|phenylalanine hydroxylase-stimulating protein|pterin-4-alpha-carbinolamine dehydratase |
Swissprots | P61457 |
Accessions | AAA35670 AAA35671 AAA35672 AAA69662 EAW54416 EAW54417 P61457 AA397961 AA736613 AF082858 AAD25732 BC006324 AAH06324 BI548743 BM724638 BQ685076 BQ897536 CR542194 CAG46991 L41559 AAA69663 M83742 XM_005269877 XP_005269934 NM_000281 NP_000272 NM_001289797 NP_001276726 |
Function | Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. |
Subcellular Location | Cytoplasm. Nucleus. Note=Cytoplasmic and/or nuclear. |
Human PCBD1 full length protein - ab100942 from Abcam
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PCBD1 / PHS Antibody Blocking Peptide - LS-E11368 from LifeSpan Bioscience
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PCBD1 / PHS Antibody Blocking Peptide - LS-E11369 from LifeSpan Bioscience
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PCBD1 / PHS Antibody Blocking Peptide - LS-E13619 from LifeSpan Bioscience
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PCBD1 / PHS Antibody Blocking Peptide - LS-E9943 from LifeSpan Bioscience
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PCBD1 Recombinant Protein - H00005092-P01 from Novus Biologicals
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Recombinant Human PCBD1 Protein - NBP1-48354 from Novus Biologicals
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PCBD1-Antibody-Center-Blocking-Peptide - BP9111c from Abgent, a WuXi AppTec company
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PHS Protein - GTX109239-pro from GeneTex
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Recombinant human Pterin-4-alpha-carbinolamine dehydratase (OPCA01286) - OPCA01286 from Aviva Systems Biology
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PCBD1 Protein (OPPA02436) - OPPA02436 from Aviva Systems Biology
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Human Pterin-4-Alpha-Carbinolamine Dehydratase protein - orb90207 from Biorbyt
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Human PCBD1 protein - orb245951 from Biorbyt
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PCBD1 Blocking Peptide - 33R-9425 from Fitzgerald
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PCBD1 protein (His tag) - 80R-1461 from Fitzgerald
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PCBD1 (1-104, His-tag) - AR09637PU-L from Acris Antibodies
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PCBD1 (1-104, His-tag) - AR09637PU-N from Acris Antibodies
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PCBD1 - H00005092-P01-10 from Acris Antibodies
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PCBD1 - H00005092-P01-25 from Acris Antibodies
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Pterin-4-Alpha-Carbinolamine Dehydratase, Human Recombinant - 228-12569-1 from RayBiotech
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Recombinant Pterin-4-Alpha-Carbinolamine Dehydratase Human - 228-12569-2 from RayBiotech
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Recombinant Pterin-4-Alpha-Carbinolamine Dehydratase Human - 228-12569-3 from RayBiotech
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PCBD1, 1-104aa, Human, His tag, E.coli - 01-1996-1 from ARP American Research Products
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Pterin-4-alpha -Carbinolamine Dehydratase, PHS, Human, Recombinant - 19-C246 from ARP American Research Products
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PCBD1 fusion protein - ag8426 from Proteintech Group
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