| Gene Symbol |
PCBD1
|
| Entrez Gene |
5092
|
| Alt Symbol |
DCOH, PCBD, PCD, PHS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
|
| Other Description |
4-alpha-hydroxy-tetrahydropterin dehydratase|6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)|dimerizing cofactor for HNF1|phenylalanine hydroxylase-stimulating protein|pterin-4-alpha-carbinolamine dehydratase
|
| Swissprots |
P61457
|
| Accessions |
AAA35670 AAA35671 AAA35672 AAA69662 EAW54416 EAW54417 P61457 AA397961 AA736613 AF082858 AAD25732 BC006324 AAH06324 BI548743 BM724638 BQ685076 BQ897536 CR542194 CAG46991 L41559 AAA69663 M83742 XM_005269877 XP_005269934 NM_000281 NP_000272 NM_001289797 NP_001276726
|
| Function |
Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity.
|
| Subcellular Location |
Cytoplasm. Nucleus. Note=Cytoplasmic and/or nuclear.
|