PTHLH

Gene Symbol	PTHLH
Entrez Gene	5744
Alt Symbol	BDE2, HHM, PLP, PTHR, PTHRP
Species	Human
Gene Type	protein-coding
Description	parathyroid hormone-like hormone
Other Description	PTH-rP|PTH-related protein|osteostatin|parathyroid hormone-like hormone preproprotein|parathyroid hormone-like related protein|parathyroid hormone-related protein
Swissprots	Q6FH74 P12272 Q15251
Accessions	AAA60221 AAA60358 AAA60359 AAA60360 CAA32480 EAW96572 EAW96573 EAW96574 EAW96575 EAW96576 P12272 AI569027 AI591151 AI760061 AK313476 BAG36261 BC005961 AAH05961 BG676028 BG679319 BG680355 BI752853 BI963162 BT007178 AAP35842 CR541882 CAG46680 DQ896393 ABM87392 EU176428 ABW03879 J03580 AAA60216 J03802 AAA60218 M26958 AAO49791 M26959 AAO49793 M26960 AAN76483 M34071 AAA60217 XM_011520774 XP_011519076 XM_011520775 XP_011519077 NM_002820 NP_002811 NM_198964 NP_945315 NM_198965 NP_945316 NM_198966 NP_945317
Function	Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath (By similarity). Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1- dependent manner through activation of Rac1. {ECO:
Subcellular Location	Cytoplasm. Nucleus. Secreted.
Tissue Specificity	Ubiquitous. Also expressed in the mammary gland.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PTHLH-Over-expression-Lysate - LY11764a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

PTHLH 293T Cell Transient Overexpression Lysate(Denatured) - H00005744-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

PTHLH 293 Cell Lysate - 400939 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Tissue Parathyroid

PTHLH 293 Cell Lysate - 403404 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Tissue Parathyroid

PTHLH 293 Cell Lysate - 403405 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Tissue Parathyroid

PTHLH/PTHrP Overexpression Lysate (Denatured) - H00005744-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

PTHLH/PTHrP Overexpression Lysate (Native) - NBL1-14948 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PTHLH/PTHrP Overexpression Lysate (Native) - NBL1-14949 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PTHLH Over-expression Lysate Product - GWB-EB9D81 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

PTHLH Over-expression Lysate Product - GWB-80F0D3 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

PTHLH Over-expression Lysate Product - GWB-6D7E52 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

PTHLH/PTHrP Overexpression Lysate (Native) - NBP2-04638 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PTHLH/PTHrP Overexpression Lysate (Native) - NBP2-04637 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PTHLH/PTHrP Overexpression Lysate (Native) - NBP2-10088 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human PTHLH Knockdown Stable Cell Line - CSC-DC012677 from Creative biogene Category Cell Line Species Human

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