PTHLH

Gene Symbol	PTHLH
Entrez Gene	5744
Alt Symbol	BDE2, HHM, PLP, PTHR, PTHRP
Species	Human
Gene Type	protein-coding
Description	parathyroid hormone-like hormone
Other Description	PTH-rP|PTH-related protein|osteostatin|parathyroid hormone-like hormone preproprotein|parathyroid hormone-like related protein|parathyroid hormone-related protein
Swissprots	Q6FH74 P12272 Q15251
Accessions	AAA60221 AAA60358 AAA60359 AAA60360 CAA32480 EAW96572 EAW96573 EAW96574 EAW96575 EAW96576 P12272 AI569027 AI591151 AI760061 AK313476 BAG36261 BC005961 AAH05961 BG676028 BG679319 BG680355 BI752853 BI963162 BT007178 AAP35842 CR541882 CAG46680 DQ896393 ABM87392 EU176428 ABW03879 J03580 AAA60216 J03802 AAA60218 M26958 AAO49791 M26959 AAO49793 M26960 AAN76483 M34071 AAA60217 XM_011520774 XP_011519076 XM_011520775 XP_011519077 NM_002820 NP_002811 NM_198964 NP_945315 NM_198965 NP_945316 NM_198966 NP_945317
Function	Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath (By similarity). Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1- dependent manner through activation of Rac1. {ECO:
Subcellular Location	Cytoplasm. Nucleus. Secreted.
Tissue Specificity	Ubiquitous. Also expressed in the mammary gland.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PTHLH full length protein - ab173029 from Abcam Category Protein Source E. coli Species Human

Human PTHLH full length protein - ab51706 from Abcam Category Protein Source E. coli Species Human

Human PTHLH peptide - ab42283 from Abcam Category Peptide Species Human

Human PTHLH peptide - ab42337 from Abcam Category Peptide Species Human

Human PTHLH peptide - ab42235 from Abcam Category Peptide Species Human

Human PTHLH protein fragment - ab50228 from Abcam Category Protein Source E. coli Species Human

PTHLH / PTHRP Antibody Blocking Peptide - LS-E11991 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PTHLH / PTHRP Blocking Peptide - LS-E8873 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PTHLH / PTHRP Antibody Blocking Peptide - LS-E8874 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PTHLH/PTHrP 15N Stable Isotope Protein - NBP2-35226 from Novus Biologicals Category Protein Prices $69.00, $149.00, $1,299.00 Sizes 5 µg, 25 µg, 1 mg Source E. coli Species Human

Recombinant Human PTHLH/PTHrP Protein - NBP2-35224 from Novus Biologicals Category Protein Prices $69.00, $169.00, $1,299.00 Sizes 10 µg, 50 µg, 1 mg Source E. coli Species Human

Recombinant Human PTHLH/PTHrP Protein - H00005744-P01 from Novus Biologicals Category Protein Prices $529.00 Sizes 25 µg Source Wheat Germ Species Human

PTHLH/PTHrP Protein - NBP1-99152 from Novus Biologicals Category Protein Species Human

Recombinant Human PTHLH/PTHrP Protein - NBP1-99388 from Novus Biologicals Category Protein Prices $195.00 Sizes 50 µg Source E. coli Species Human

PTHLH-Antibody-Center-Blocking-Peptide - BP7336c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PTHLH-Antibody-N-term-Blocking-Peptide - BP7336a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PTHrP Recombinant Protein - GTX48381-PRO from GeneTex Category Protein Prices $299.00 Sizes 50 μg Source E. coli Species Human

SYNTHETIC Human PARATHYROID HORMONE RELATED PEPTIDE Protein (OPSA10581) - OPSA10581 from Aviva Systems Biology Category Protein Prices $245.00 Sizes 100 µg Species Human

Human PTHrP protein - orb223922 from Biorbyt Category Protein Prices $221.00, $357.00, $366.00, $578.00 Sizes 10 μg, 50 μg, 100 μg, 250 μg Species Human

Human PTHLH protein - orb244473 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human PTHrP protein - orb169114 from Biorbyt Category Protein Prices $187.00, $323.00 Sizes 10 μg, 50 μg Species Human

Human PTHrP protein - orb223923 from Biorbyt Category Protein Prices $221.00, $357.00, $434.00, $629.00 Sizes 5 μg, 25 μg, 100 μg, 250 μg Species Human

Human, Bovine, Dog, Horse, Mouse, Rabbit, Rat Osteostatin (1-5) peptide - orb70918 from Biorbyt Category Peptide Prices $264.00 Sizes 5 mg Species Human, Mouse, Rat, Rabbit, Bovine, Dog, Horse

PTHLH Blocking Peptide - 33R-10147 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PTHrP protein - 30R-AP028 from Fitzgerald Category Protein Prices $225.00 Sizes 10 µg Source E.coli

Search more