SPI1

Gene Symbol	SPI1
Entrez Gene	6688
Alt Symbol	OF, PU.1, SFPI1, SPI-1, SPI-A
Species	Human
Gene Type	protein-coding
Description	Spi-1 proto-oncogene
Other Description	31 kDa transforming protein|31 kDa-transforming protein|hematopoietic transcription factor PU.1|spleen focus forming virus (SFFV) proviral integration oncogene spi1|transcription factor PU.1
Swissprots	P17947
Accessions	AAC50247 CDL93508 EAW67924 EAW67925 EAW67926 P17947 AK310065 BC111379 AAI11380 BI519776 BI909430 BM561863 BP271276 CD368431 HG503768 HG503769 HG503770 X52056 CAA36281 XM_011520305 XP_011518607 XM_011520306 XP_011518608 XM_011520307 XP_011518609 XM_011520308 XP_011518610 NM_001080547 NP_001074016 NM_003120 NP_003111
Function	Binds to the PU-box, a purine-rich DNA sequence (5'- GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B- cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00237, ECO:0000269|PubMed:23166356}.
Top Pathways	Acute myeloid leukemia, Osteoclast differentiation, HTLV-I infection, Epstein-Barr virus infection, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PU.1/Spi1 full length protein - ab202185 from Abcam Category Protein Source E. coli Species Human

Human PU.1/Spi1 protein fragment - ab152701 from Abcam Category Protein Source Wheat germ Species Human

SPI1 / PU.1 Antibody Blocking Peptide - LS-E3647 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPI1 / PU.1 Antibody Blocking Peptide - LS-E10978 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPI1 / PU.1 Antibody Blocking Peptide - LS-E13736 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPI1 / PU.1 Antibody Blocking Peptide - LS-E13596 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPI1 / PU.1 Antibody Blocking Peptide - LS-E13320 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPI1 / PU.1 Antibody Blocking Peptide - LS-E26660 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PU.1/Spi-1 Recombinant Protein - H00006688-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PU.1/Spi-1 Partial Recombinant Protein - H00006688-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

SPI1-Antibody-C-term-Blocking-Peptide - BP14850b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PU.1 blocking peptide - GTX88620-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Rat

Recombinant human Transcription factor PU.1 (OPCA01108) - OPCA01108 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human SPI1 protein - orb245652 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

SPI1 Immunizing peptide - orb54886 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

SFPI1 Blocking Peptide - 33R-6668 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SPI1 protein (His tag) - 80R-4103 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

PU.1/SPi1 Peptide - AC21-1497-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SPI1 / PU.1 (1-271, His-tag) - AR51789PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

SPI1 / PU.1 (1-271, His-tag) - AR51789PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

SPI1 / PU.1 - H00006688-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SPI1 / PU.1 - H00006688-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SPI1 / PU.1 - H00006688-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SPI1 / PU.1 - H00006688-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SPI1 Peptide - 42-746P from ProSci Category Peptide Species Human

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