HTATIP2

Gene Symbol	HTATIP2
Entrez Gene	10553
Alt Symbol	CC3, SDR44U1, TIP30
Species	Human
Gene Type	protein-coding
Description	HIV-1 Tat interactive protein 2, 30kDa
Other Description	30 kDa HIV-1 TAT-interacting protein|HIV-1 TAT-interactive protein 2|Tat-interacting protein (30kD)|oxidoreductase HTATIP2|short chain dehydrogenase/reductase family 44U, member 1
Swissprots	O95345 D3DQY8 Q9BUP3 A8K7S7 O60520 O15383 Q53GG2 Q53GC1 Q6IBI3
Accessions	EAW68337 EAW68338 EAW68339 EAW68340 EAW68341 Q9BUP3 AF039103 AAC39694 AF092095 AAC78331 AI193677 AK130473 AK222969 BAD96689 AK223010 BAD96730 AK292092 BAF84781 AW963626 BC002439 AAH02439 BC015358 AAH15358 BF681178 BP382529 CR456821 CAG33102 DB450790 EU446982 ABZ92511 U69161 AAB84360 NM_001098520 NP_001091990 NM_001098521 NP_001091991 NM_001098522 NP_001091992 NM_001098523 NP_001091993 NM_006410 NP_006401
Function	Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. {ECO:0000269|PubMed:10611237, ECO:0000269|PubMed:11313954, ECO:0000269|PubMed:15282309, ECO:0000269|PubMed:9174052}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15282309}. Nucleus envelope {ECO:0000269|PubMed:15282309}.
Tissue Specificity	Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain. Not expressed or low levels in variant small cell lung carcinomas, 33% of hepatocellular carcinomas and neuroblastomas. {ECO:0000269|PubMed:14695192, ECO:0000269|PubMed:9174052}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HTATIP2 293T Cell Transient Overexpression Lysate(Denatured) - H00010553-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

HTATIP2 overexpression lysate - LY420619 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

HTATIP2 overexpression lysate - LY420620 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

HTATIP2 overexpression lysate - LY420621 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

TIP30 Overexpression Lysate (Native) - NBP2-10921 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TIP30 Overexpression Lysate (Native) - NBP2-10920 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TIP30 Overexpression Lysate (Native) - NBP2-10414 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TIP30 Overexpression Lysate (Denatured) - H00010553-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human HTATIP2 Knockdown Stable Cell Line - CSC-DC007333 from Creative biogene Category Cell Line Species Human

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