HTATIP2

Gene Symbol HTATIP2
Entrez Gene 10553
Alt Symbol CC3, SDR44U1, TIP30
Species Human
Gene Type protein-coding
Description HIV-1 Tat interactive protein 2, 30kDa
Other Description 30 kDa HIV-1 TAT-interacting protein|HIV-1 TAT-interactive protein 2|Tat-interacting protein (30kD)|oxidoreductase HTATIP2|short chain dehydrogenase/reductase family 44U, member 1
Swissprots O95345 D3DQY8 Q9BUP3 A8K7S7 O60520 O15383 Q53GG2 Q53GC1 Q6IBI3
Accessions EAW68337 EAW68338 EAW68339 EAW68340 EAW68341 Q9BUP3 AF039103 AAC39694 AF092095 AAC78331 AI193677 AK130473 AK222969 BAD96689 AK223010 BAD96730 AK292092 BAF84781 AW963626 BC002439 AAH02439 BC015358 AAH15358 BF681178 BP382529 CR456821 CAG33102 DB450790 EU446982 ABZ92511 U69161 AAB84360 NM_001098520 NP_001091990 NM_001098521 NP_001091991 NM_001098522 NP_001091992 NM_001098523 NP_001091993 NM_006410 NP_006401
Function Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. {ECO:0000269|PubMed:10611237, ECO:0000269|PubMed:11313954, ECO:0000269|PubMed:15282309, ECO:0000269|PubMed:9174052}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15282309}. Nucleus envelope {ECO:0000269|PubMed:15282309}.
Tissue Specificity Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain. Not expressed or low levels in variant small cell lung carcinomas, 33% of hepatocellular carcinomas and neuroblastomas. {ECO:0000269|PubMed:14695192, ECO:0000269|PubMed:9174052}.

HTATIP2/TIP30 Antibody - 14614 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using HTATIP2/TIP30 Antibody.

TIP30 (E-16) - sc-55343 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TIP30 (E-16): sc-55343. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung tissue showing nuclear and cytoplasmic staining of pneumocytes and macrophages.

Anti-TIP30 antibody - ab192775 from Abcam

Prices $407.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of formalin-fixed, paraffin-embedded human small intestine tissue labeling TIP30 with ab192775 at 5 µg/ml.

Anti-TIP30 antibody - ab125726 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ab125726, at 1/500 dilution, staining TIP30 (Green) in Paraformaldehyde-fixed HeLa cells by Immunocytochemistry/Immunofluorescence.

Anti-TIP30 antibody - ab10268 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TIP30 antibody [EPR13179] - ab177961 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13179
Flow cytometric analysis of permeabilized HeLa cells labeling TIP30 using ab177961 at 1/10 dilution (red) or a rabbit IgG (negative) (green).

Anti-TIP30 antibody [EPR13185] - ab181378 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13185
All lanes : Anti-TIP30 antibody [EPR13185] (ab181378) at 1/10000 dilutionLane 1 : Human fetal liver tissue lysateLane 2 : HeLa cell lysateLane 3 : A431 cell lysateLane 4 : A549 cell lysateLane 5 : SW480 cell lysateLysates/proteins at 10 µg per lane.

Anti-TIP30 / HTATIP2 Antibody IHC-plus™ - LS-B10900 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-TIP30 / HTATIP2 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10900 concentration 5 ug/ml.

Anti-TIP30 / HTATIP2 Antibody (clone 422D2a) - LS-C184772 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 422D2a

Anti-TIP30 / HTATIP2 Antibody (aa45-74, APC) - LS-C215192 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIP30 / HTATIP2 Antibody (aa45-74, AP) - LS-C215193 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIP30 / HTATIP2 Antibody (aa45-74, FITC) - LS-C215195 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIP30 / HTATIP2 Antibody (aa45-74, Azide-free, HRP) - LS-C215196 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIP30 / HTATIP2 Antibody (aa45-74, Biotin) - LS-C215194 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIP30 / HTATIP2 Antibody (aa45-74, PE) - LS-C215197 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIP30 / HTATIP2 Antibody - LS-C308348 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TIP30 / HTATIP2 Antibody (aa44-74) - LS-C322122 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIP30 / HTATIP2 Antibody (clone 422D2a) - LS-C342793 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 422D2a

Anti-TIP30 / HTATIP2 Antibody - LS-C341888 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TIP30 / HTATIP2 Antibody (N-Terminus) - LS-C30014 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal Liver Lysate

Anti-TIP30 / HTATIP2 Antibody (aa2-15) - LS-C55598 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (1 ug/ml) of Human Lung lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-TIP30 / HTATIP2 Antibody (aa30-79) - LS-C30651 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HTATIP2 / TIP30 antibody LS-C30651 was used in IHC to stain formalin-fixed, paraffin-embedded human lung.

Anti-TIP30 / HTATIP2 Antibody (aa45-74) - LS-C165078 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HTATIP2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

TIP30 Antibody - NBP1-88170 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TIP30 Antibody - NBP2-20646 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TIP30 Antibody [NBP2-20646] - Sample (30 ug of whole cell lysate) A: A431 B: HeLa 12% SDS PAGE gel, diluted at 1:5000.
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