HTATIP2

Gene Symbol	HTATIP2
Entrez Gene	10553
Alt Symbol	CC3, SDR44U1, TIP30
Species	Human
Gene Type	protein-coding
Description	HIV-1 Tat interactive protein 2, 30kDa
Other Description	30 kDa HIV-1 TAT-interacting protein|HIV-1 TAT-interactive protein 2|Tat-interacting protein (30kD)|oxidoreductase HTATIP2|short chain dehydrogenase/reductase family 44U, member 1
Swissprots	O95345 D3DQY8 Q9BUP3 A8K7S7 O60520 O15383 Q53GG2 Q53GC1 Q6IBI3
Accessions	EAW68337 EAW68338 EAW68339 EAW68340 EAW68341 Q9BUP3 AF039103 AAC39694 AF092095 AAC78331 AI193677 AK130473 AK222969 BAD96689 AK223010 BAD96730 AK292092 BAF84781 AW963626 BC002439 AAH02439 BC015358 AAH15358 BF681178 BP382529 CR456821 CAG33102 DB450790 EU446982 ABZ92511 U69161 AAB84360 NM_001098520 NP_001091990 NM_001098521 NP_001091991 NM_001098522 NP_001091992 NM_001098523 NP_001091993 NM_006410 NP_006401
Function	Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. {ECO:0000269|PubMed:10611237, ECO:0000269|PubMed:11313954, ECO:0000269|PubMed:15282309, ECO:0000269|PubMed:9174052}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15282309}. Nucleus envelope {ECO:0000269|PubMed:15282309}.
Tissue Specificity	Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain. Not expressed or low levels in variant small cell lung carcinomas, 33% of hepatocellular carcinomas and neuroblastomas. {ECO:0000269|PubMed:14695192, ECO:0000269|PubMed:9174052}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TIP30 full length protein - ab98078 from Abcam Category Protein Source E. coli Species Human

Human TIP30 full length protein - ab117665 from Abcam Category Protein Source E. coli Species Human

Human TIP30 peptide - ab74501 from Abcam Category Peptide

Human TIP30 peptide - ab23202 from Abcam Category Peptide Species Human

TIP30 / HTATIP2 Antibody Blocking Peptide - LS-E3565 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TIP30 / HTATIP2 Antibody Blocking Peptide - LS-E25700 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TIP30 / HTATIP2 Antibody Blocking Peptide - LS-E11532 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TIP30 Recombinant Protein - H00010553-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

TIP30 Recombinant Protein - H00010553-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human TIP30 Protein - NBP1-50847 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

HTATIP2-Antibody-N-term-Blocking-Peptide - BP14762a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TIP30 blocking peptide - GTX10268-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

HTATIP2 Protein (OPPA02315) - OPPA02315 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human HIV-1 Tat Interactive Protein 2 protein - orb90149 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli

HTATIP2 Immunizing peptide - orb16732 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

HTATIP2 protein (His tag) - 80R-1393 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

TIP30 Peptide - AC21-0530-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

HTATIP2 (1-242, His-tag) - AR09568PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

HTATIP2 (1-242, His-tag) - AR09568PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

HTATIP2 - H00010553-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

HTATIP2 - H00010553-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HTATIP2 - H00010553-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

HTATIP2 - H00010553-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

HTATIP2 - H00010553-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

HTATIP2, 1-242aa, Human, His tag, E.coli - 01-2149 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

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