HTATIP2

Gene Symbol HTATIP2
Entrez Gene 10553
Alt Symbol CC3, SDR44U1, TIP30
Species Human
Gene Type protein-coding
Description HIV-1 Tat interactive protein 2, 30kDa
Other Description 30 kDa HIV-1 TAT-interacting protein|HIV-1 TAT-interactive protein 2|Tat-interacting protein (30kD)|oxidoreductase HTATIP2|short chain dehydrogenase/reductase family 44U, member 1
Swissprots O95345 D3DQY8 Q9BUP3 A8K7S7 O60520 O15383 Q53GG2 Q53GC1 Q6IBI3
Accessions EAW68337 EAW68338 EAW68339 EAW68340 EAW68341 Q9BUP3 AF039103 AAC39694 AF092095 AAC78331 AI193677 AK130473 AK222969 BAD96689 AK223010 BAD96730 AK292092 BAF84781 AW963626 BC002439 AAH02439 BC015358 AAH15358 BF681178 BP382529 CR456821 CAG33102 DB450790 EU446982 ABZ92511 U69161 AAB84360 NM_001098520 NP_001091990 NM_001098521 NP_001091991 NM_001098522 NP_001091992 NM_001098523 NP_001091993 NM_006410 NP_006401
Function Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. {ECO:0000269|PubMed:10611237, ECO:0000269|PubMed:11313954, ECO:0000269|PubMed:15282309, ECO:0000269|PubMed:9174052}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15282309}. Nucleus envelope {ECO:0000269|PubMed:15282309}.
Tissue Specificity Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain. Not expressed or low levels in variant small cell lung carcinomas, 33% of hepatocellular carcinomas and neuroblastomas. {ECO:0000269|PubMed:14695192, ECO:0000269|PubMed:9174052}.

TIP30 CRISPR/Cas9 KO Plasmid (h) - sc-406742 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP30 HDR Plasmid (h) - sc-406742-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP30 Double Nickase Plasmid (h) - sc-406742-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP30 Double Nickase Plasmid (h2) - sc-406742-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP30 CRISPR Activation Plasmid (h) - sc-406742-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP30 CRISPR Activation Plasmid (h2) - sc-406742-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP30 Lentiviral Activation Particles (h) - sc-406742-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP30 Lentiviral Activation Particles (h2) - sc-406742-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP30 siRNA (h) - sc-63131 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIP30 shRNA Plasmid (h) - sc-63131-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIP30 shRNA (h) Lentiviral Particles - sc-63131-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIP30 RNAi - H00010553-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU047111 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10387 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10387 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05083 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05083

HTATIP2 siRNA (Human) - CRH7174 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HTATIP2 - MBS8220207 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TIP30 CRISPR/Cas9 KO Plasmid (h2) - sc-406742-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP30 HDR Plasmid (h2) - sc-406742-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human HTATIP (NM_006410.4) - SHH315817 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HTATIP2(NM_006410.4) - SHH135197 from Creative biogene

Category siRNA
Species Reactivities Human

Human HTATIP2 siRNA - orb267676 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HTATIP2 shRNA Plasmid (Human) - CHH7174 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HTATIP2 miRNA 3'UTR clone - MiUTR1H-04750 from Creative biogene

Species Reactivities Human
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