Gene Symbol | PPP1R13B |
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Entrez Gene | 23368 |
Alt Symbol | ASPP1, p53BP2-like, p85 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 1, regulatory subunit 13B |
Other Description | apoptosis-stimulating of p53 protein 1|apoptosis-stimulating protein of p53, 1|protein phosphatase 1 regulatory subunit 13B|protein phosphatase 1, regulatory (inhibitor) subunit 13B |
Swissprots | Q96KQ4 B2RMX5 O94870 |
Accessions | CCQ43503 EAW81845 EAW81846 EAW81847 Q96KQ4 AB018314 BAA34491 AJ318887 CAC83011 AK021580 AK023188 BAG51166 AK125374 AK125913 BAC86342 AK307149 AW295594 BC035446 BC047639 BC136527 AAI36528 DB461586 XM_005267487 XP_005267544 XM_011536592 XP_011534894 XM_011536593 XP_011534895 XM_011536594 XP_011534896 XM_011536595 XP_011534897 XM_011536596 XP_011534898 XM_011536597 XP_011534899 XM_011536598 XP_011534900 XR_245676 XR_943410 XR_943411 XR_943412 XR_943413 NM_015316 NP_056131 |
Function | Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. {ECO:0000269|PubMed:11684014}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11684014}. Nucleus {ECO:0000269|PubMed:11684014}. Note=Predominantly cytoplasmic. Some fraction is nuclear. |
Tissue Specificity | Reduced expression in breast carcinomas expressing a wild-type TP53 protein. {ECO:0000269|PubMed:11684014}. |
PPP1R13B Antibody Blocking Peptide - LS-E4820 from LifeSpan Bioscience
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PPP1R13B Antibody Blocking Peptide - LS-E17365 from LifeSpan Bioscience
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PPP1R13B-Antibody-Center-Blocking-Peptide - BP17200c from Abgent, a WuXi AppTec company
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PPP1R13B Blocking Peptide - 33R-2400 from Fitzgerald
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PPP1R13B Blocking Peptide - abx161199 from Abbexa
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PPP1R13B - H00023368-Q01-10 from Acris Antibodies
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PPP1R13B - H00023368-Q01-25 from Acris Antibodies
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PPP1R13B Blocking Peptide - CBP3698 from Cohesion Biosciences
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Recombinant Human Apoptosis-stimulating of p53 protein 1(PPP1R13B) ,partial - CSB-YP853449HU CSB-EP853449HU CSB-BP853449HU CSB-MP853449HU from Cusabio
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PPP1R13B Blocking Peptide - CBP4165 from Cohesion Biosciences
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PPP1R13B Blocking Peptide - abx161376 from Abbexa
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PPP1R13B - TP321172 from Acris Antibodies
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Apoptosis-stimulating of p53 protein 1(PPP1R13B) ,partial, Recombinant Protein - MBS1427544 from MyBioSource
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ASPP1 Recombinant Protein Antigen - NBP1-90078PEP from Novus Biologicals
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PPP1R13B-Antibody-N-term-Blocking-Peptide - BP7581a from Abgent, a WuXi AppTec company
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PPP1R13B Peptide, Human - M34GP12234H from Creative Peptides
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PPP1R13B peptide - orb234573 from Biorbyt
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