PPP1R13B

Gene Symbol PPP1R13B
Entrez Gene 23368
Alt Symbol ASPP1, p53BP2-like, p85
Species Human
Gene Type protein-coding
Description protein phosphatase 1, regulatory subunit 13B
Other Description apoptosis-stimulating of p53 protein 1|apoptosis-stimulating protein of p53, 1|protein phosphatase 1 regulatory subunit 13B|protein phosphatase 1, regulatory (inhibitor) subunit 13B
Swissprots Q96KQ4 B2RMX5 O94870
Accessions CCQ43503 EAW81845 EAW81846 EAW81847 Q96KQ4 AB018314 BAA34491 AJ318887 CAC83011 AK021580 AK023188 BAG51166 AK125374 AK125913 BAC86342 AK307149 AW295594 BC035446 BC047639 BC136527 AAI36528 DB461586 XM_005267487 XP_005267544 XM_011536592 XP_011534894 XM_011536593 XP_011534895 XM_011536594 XP_011534896 XM_011536595 XP_011534897 XM_011536596 XP_011534898 XM_011536597 XP_011534899 XM_011536598 XP_011534900 XR_245676 XR_943410 XR_943411 XR_943412 XR_943413 NM_015316 NP_056131
Function Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. {ECO:0000269|PubMed:11684014}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11684014}. Nucleus {ECO:0000269|PubMed:11684014}. Note=Predominantly cytoplasmic. Some fraction is nuclear.
Tissue Specificity Reduced expression in breast carcinomas expressing a wild-type TP53 protein. {ECO:0000269|PubMed:11684014}.

ASPP1 (G-20) - sc-50890 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ASPP1 (G-20): sc-50890. Western blot analysis of ASPP1 expression in Caki-1 (A), ZR-75-1 (B), U-2 OS (C), MCF7 (D), HeLa (E) and SK-BR-3 (F) whole cell lysates.

ASPP1 (L-15) - sc-50891 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ASPP1 (LX011) - sc-53903 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ASPP1 (LX011): sc-53903. Western blot analysis of ASPP1 expression in WI 38 (A,C) and Saos-2 (B,D) whole cell lysates under reducing (A,B) and non-reducing (C,D) conditions.

ASPP1 (M-18) - sc-10921 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ASPP1 (M-18): sc-10921. Western blot analysis of ASPP1 expression in HeLa (A) and WI-38 (B) whole cell lysates.

ASPP1 (N-13) - sc-50892 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ASPP1 (S-18) - sc-50893 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ASPP1 (54.2) - sc-53860 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Anti-ASPP1 antibody - ab71163 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ASPP1 antibody (ab71163) at 0.1 µg/mlLane 1 : Whole cell lysate from 293T cells at 50 µgLane 2 : Whole cell lysate from 293T cells at 15 µgLane 3 : Whole cell lysate from 293T cells at 5 µgLane 4 : Whole cell lysate from Hela cells at 50 µgdeveloped using the ECL technique

Anti-ASPP1 antibody - ab51831 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ASPP1 antibody (ab51831) at 1/1000 dilutionLane 1 : Non-transfected controlLane 2 : MCF7 cells over expressing ASPP1Lane 3 : MCF7 cells overexpressing ASPP2

Anti-ASPP1 antibody - ab71164 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ASPP1 antibody (ab71164) at 0.4 µg/mlLane 1 : Whole cell lysate from 293T cells at 50 µgLane 2 : Whole cell lysate from 293T cells at 15 µgLane 3 : Whole cell lysate from 293T cells at 5 µgLane 4 : Whole cell lysate from Hela cells at 50 µgdeveloped using the ECL technique

Anti-ASPP1 antibody - ab85535 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ASPP1 antibody (ab85535) at 1 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PPP1R13B Antibody (aa623-652) - LS-C158711 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PPP1R13B Antibody western blot of SK-BR-3 cell line lysates (35 ug/lane). The PPP1R13B antibody detected the PPP1R13B protein (arrow).

Anti-PPP1R13B Antibody (aa50-100) - LS-C74332 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PPP1R13B Antibody (aa475-525) - LS-C74333 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PPP1R13B Antibody (Internal) - LS-C60111 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ASPP1 Antibody - Western Blot. Western blot of affinity purified anti-ASPP1 to detect over-expressed ASPP1 in MCF-7 cells (lane 2, arrowhead). Lane 1 is a non-transfected control. Lane 3 is MCF-7 cells over-expressing ASPP2. Cell extracts were electrophoresed and transferred to nitrocellulose. The membrane was probed with the primary antibody at a 1:1000 dilution. The identity of the lower MW band at approximately 50kD is unknown. Primary experimental data indicate that the unknown band intensifies in extracts from p53 siRNA knockdown cells. Personal Communication, H. Yang, Univ. Oklahoma, Oklahoma City, OK.

Anti-PPP1R13B Antibody (aa623-652, AP) - LS-C207505 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R13B Antibody (aa623-652, APC) - LS-C207506 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R13B Antibody (aa623-652, Biotin) - LS-C207507 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R13B Antibody (aa623-652, FITC) - LS-C207508 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R13B Antibody (aa623-652, Azide-free, HRP) - LS-C207509 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R13B Antibody (aa623-652, PE) - LS-C207510 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R13B Antibody (aa50-100) - LS-C287755 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R13B Antibody (aa475-525) - LS-C287756 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R13B Antibody (aa622-652) - LS-C324233 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R13B Antibody (aa900-949) - LS-C102276 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PPP1R13B antibody LS-C102276 Western blot of HepG2 cell lysate.
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