Gene Symbol | PTGR1 |
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Entrez Gene | 22949 |
Alt Symbol | LTB4DH, PGR1, ZADH3 |
Species | Human |
Gene Type | protein-coding |
Description | prostaglandin reductase 1 |
Other Description | 15-oxoprostaglandin 13-reductase|NADP-dependent leukotriene B4 12-hydroxydehydrogenase|PRG-1|leukotriene B4 12-hydroxydehydrogenase|zinc binding alcohol dehydrogenase domain containing 3 |
Swissprots | B4DPK3 A8K0N2 Q14914 Q9H1X6 Q8IYQ0 F5GY50 |
Accessions | EAW59074 EAW59075 EAW59076 EAW59077 EAW59078 Q14914 AA876375 AK091948 AK289597 BAF82286 AK298379 BAG60615 AK309450 AK309866 BC035228 AAH35228 D49387 BAA08382 XM_011518394 XP_011516696 XM_011518395 XP_011516697 XR_929738 NM_001146108 NP_001139580 NM_001146109 NP_001139581 NM_012212 NP_036344 |
Function | Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. {ECO:0000250}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | High expression in the kidney, liver, and intestine but not in leukocytes. {ECO:0000269|PubMed:8576264}. |
LTB4DH (S-12) - sc-137587 from Santa Cruz Biotechnology
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Anti-PTGR1 antibody - ab107005 from Abcam
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Anti-PTGR1 antibody - ab194479 from Abcam
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Anti-PTGR1 antibody - ab105530 from Abcam
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Anti-PTGR1 antibody - ab137957 from Abcam
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Anti-PTGR1 antibody [EPR13451-10] - ab181131 from Abcam
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Anti-PGR1 / GPR153 Antibody (aa52-80, APC) - LS-C214822 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (aa52-80, AP) - LS-C214820 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (aa52-80, Biotin) - LS-C214823 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (aa52-80, Azide-free, HRP) - LS-C214824 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (aa52-80, FITC) - LS-C214825 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (aa52-80, PE) - LS-C214826 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (aa185-234) - LS-C292014 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (aa51-80) - LS-C321739 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (Glu234) - LS-C340842 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (aa195-244) - LS-C120614 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (aa291-340) - LS-C120695 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (aa52-80) - LS-C166628 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (C-Terminus) IHC-plus⢠- LS-A3140 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (C-Terminus) IHC-plus⢠- LS-A3141 from LifeSpan Bioscience
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Anti-PGR1 / GPR153 Antibody (Extracellular Domain) IHC-plus⢠- LS-A2032 from LifeSpan Bioscience
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Anti-PTGR1 / LTB4DH Antibody (N-Terminus) - LS-C81951 from LifeSpan Bioscience
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Anti-PTGR1 / LTB4DH Antibody (aa75-124) - LS-C120130 from LifeSpan Bioscience
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Anti-PTGR1 / LTB4DH Antibody (aa184-214, AP) - LS-C284855 from LifeSpan Bioscience
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Anti-PTGR1 / LTB4DH Antibody (aa184-214, APC) - LS-C284856 from LifeSpan Bioscience
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