PTGR1

Gene Symbol	PTGR1
Entrez Gene	22949
Alt Symbol	LTB4DH, PGR1, ZADH3
Species	Human
Gene Type	protein-coding
Description	prostaglandin reductase 1
Other Description	15-oxoprostaglandin 13-reductase|NADP-dependent leukotriene B4 12-hydroxydehydrogenase|PRG-1|leukotriene B4 12-hydroxydehydrogenase|zinc binding alcohol dehydrogenase domain containing 3
Swissprots	B4DPK3 A8K0N2 Q14914 Q9H1X6 Q8IYQ0 F5GY50
Accessions	EAW59074 EAW59075 EAW59076 EAW59077 EAW59078 Q14914 AA876375 AK091948 AK289597 BAF82286 AK298379 BAG60615 AK309450 AK309866 BC035228 AAH35228 D49387 BAA08382 XM_011518394 XP_011516696 XM_011518395 XP_011516697 XR_929738 NM_001146108 NP_001139580 NM_001146109 NP_001139581 NM_012212 NP_036344
Function	Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. {ECO:0000250}.
Subcellular Location	Cytoplasm.
Tissue Specificity	High expression in the kidney, liver, and intestine but not in leukocytes. {ECO:0000269|PubMed:8576264}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PTGR1 overexpression lysate - LY415903 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PTGR1 overexpression lysate - LY431263 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PTGR1 overexpression lysate - LY431853 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PTGR1 293 Cell Lysate - 407464 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PGR1 Overexpression Lysate (Native) - NBL1-14941 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PTGR1 Over-expression Lysate Product - GWB-8502AB from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

PGR1 Overexpression Lysate (Native) - NBP2-10714 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Panoply™ Human PTGR1 Knockdown Stable Cell Line - CSC-DC012669 from Creative biogene Category Cell Line Species Human

Human PTGR1 Knockout Cell Line-HeLa - CSC-RT1390 from Creative biogene Category Cell Line Species Human

PTGR1 KO Cell Lysate-HeLa - CLKO-1242 from Creative biogene Category Cell Lysate

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