PTGR1

Gene Symbol PTGR1
Entrez Gene 22949
Alt Symbol LTB4DH, PGR1, ZADH3
Species Human
Gene Type protein-coding
Description prostaglandin reductase 1
Other Description 15-oxoprostaglandin 13-reductase|NADP-dependent leukotriene B4 12-hydroxydehydrogenase|PRG-1|leukotriene B4 12-hydroxydehydrogenase|zinc binding alcohol dehydrogenase domain containing 3
Swissprots B4DPK3 A8K0N2 Q14914 Q9H1X6 Q8IYQ0 F5GY50
Accessions EAW59074 EAW59075 EAW59076 EAW59077 EAW59078 Q14914 AA876375 AK091948 AK289597 BAF82286 AK298379 BAG60615 AK309450 AK309866 BC035228 AAH35228 D49387 BAA08382 XM_011518394 XP_011516696 XM_011518395 XP_011516697 XR_929738 NM_001146108 NP_001139580 NM_001146109 NP_001139581 NM_012212 NP_036344
Function Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. {ECO:0000250}.
Subcellular Location Cytoplasm.
Tissue Specificity High expression in the kidney, liver, and intestine but not in leukocytes. {ECO:0000269|PubMed:8576264}.

PTGR1 - MBS1268272 from MyBioSource

Species Human
Accession BC035228

Human PTGR1 cDNA clone(NM_001146108.1) - CDFH015476 from Creative Biomart

Species Human
Accession NM_001146108.1

Human PTGR1 cDNA clone(NM_001146109.1) - CDFH015477 from Creative Biomart

Species Human
Accession NM_001146109.1

Human PTGR1 ORF Clone(NM_001146108.1) - CDCR353270 from Creative Biomart

Species Human
Accession NM_001146108.1

Human PTGR1 ORF Clone(NM_001146109.1) - CDCR353271 from Creative Biomart

Species Human
Accession NM_001146109.1

Human PTGR1 ORF Clone(NM_001146109.1) - CDCR353272 from Creative Biomart

Species Human
Accession NM_001146109.1

Human PTGR1 ORF Clone(NM_001146108.1) - CDCR353274 from Creative Biomart

Species Human
Accession NM_001146108.1

Human PTGR1 ORF clone (NM_001146108.1) - CDCL149674 from Creative biogene

Species Human

Human PTGR1 ORF clone (NM_001146109.1) - CDCL149676 from Creative biogene

Species Human

Human PTGR1 ORF Clone (BC035228) - CDCS408589 from Creative biogene

Species Human
Accession Q14914

Human PTGR1 cDNA Clone(NM_001146108.1) - CDFH015476 from Creative biogene

Species Human

Human PTGR1 cDNA Clone(NM_001146109.1) - CDFH015477 from Creative biogene

Species Human
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