HFE2

Gene Symbol HFE2
Entrez Gene 148738
Alt Symbol HFE2A, HJV, JH, RGMC
Species Human
Gene Type protein-coding
Description hemochromatosis type 2 (juvenile)
Other Description RGM domain family member C|haemojuvelin|hemochromatosis type 2 protein|hemojuvelin|repulsive guidance molecule c
Swissprots Q6ZVN8 Q8WVJ5 Q2PQ63 B1ALI7 Q8NAH2 Q6IMF6
Accessions ABC40718 CAI22091 CAI22092 CAI22349 CAI22350 CAN86494 CAO00462 CAX62674 CAX86829 CEF39436 EAW71407 EAW71408 EAW71409 Q6ZVN8 AA479148 AK092682 BAC03944 AK092692 BAC03947 AK096905 BAC04890 AK124273 BAC85823 AK223575 AK290831 BAF83520 AK292742 BAF85431 AK315852 BAF98743 AY372521 AAR22390 BC017926 AAH17926 BC085604 AAH85604 DB035674 HQ447765 ADQ32250 XM_005272932 XP_005272989 NM_145277 NP_660320 NM_202004 NP_973733 NM_213652 NP_998817 NM_213653 NP_998818
Function Member of the repulsive guidance molecule (RGM) family. Involved in iron metabolism. Acts as a bone morphogenetic protein (BMP) coreceptor (By similarity). Enhancement of BMP signaling regulates hepcidin (HAMP) expression and iron metabolism (By similarity). May cooperate with hepcidin to restrict iron absorption in the gut. Could represent the cellular receptor for hepcidin. {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
Tissue Specificity Adult and fetal liver, heart, and skeletal muscle. {ECO:0000269|PubMed:14647275}.

RGMc (H-38) - sc-67054 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RGMc (H-38): sc-67054. Western blot analysis of RGMc expression in non-transfected 293T: sc-117752 (A), human RGMc transfected 293T: sc-111637 (B) and Hep G2 (C) whole cell lysates.

RGMc (E-18) - sc-46491 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RGMc (C-19) - sc-46490 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RGMc (A-16) - sc-46489 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Repulsive Guidance Molecule C antibody - ab104492 from Abcam

Prices $392.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Repulsive Guidance Molecule C antibody (ab104492) at 1/500 dilution + Mouse spleen tissue lysate at 50 µg

Anti-Repulsive Guidance Molecule C antibody - ab187529 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Repulsive Guidance Molecule C antibody (ab187529) at 1/500 dilutionLane 1 : HeLa cell extractLane 2 : PC3 cell extract

Anti-Repulsive Guidance Molecule C antibody - ab86991 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Repulsive Guidance Molecule C antibody (ab86991) at 1 µg/mlLane 1 : Rat Embryonic Skeletal MuscleLane 2 : Rat Post Natal Day Zero Skeletal MuscleLane 3 : Rat Embryonic Day 18 Heartdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Repulsive Guidance Molecule C antibody [Fery-1] - ab54431 from Abcam

Prices $379.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone Fery-1
All lanes : Anti-Repulsive Guidance Molecule C antibody [Fery-1] (ab54431) at 1/1000 dilutionLane 1 : embryonic day 16 mouse muscleLane 2 : adult mouse heartLysates/proteins at 20 µg per lane.SecondaryHRP conjugated at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-HFE2 / Hemojuvelin Antibody (aa1-313) - LS-C129760 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa308-338, APC) - LS-C236202 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa308-338, AP) - LS-C236200 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa308-338, Biotin) - LS-C236203 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa308-338, FITC) - LS-C236204 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa308-338, PE) - LS-C236205 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa134-162, AP) - LS-C236206 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa134-162, APC) - LS-C236207 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa35-84) - LS-C116550 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HFE2 antibody LS-C116550 Western blot of HT1080 cell lysate.

Anti-HFE2 / Hemojuvelin Antibody (aa134-162, Biotin) - LS-C236208 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa134-162, FITC) - LS-C236209 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa134-162, PE) - LS-C236213 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa308-338, Azide-free, HRP) - LS-C249184 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa134-162, Azide-free, HRP) - LS-C249185 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (clone 1C12) IHC-plus™ - LS-B7222 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1C12
Anti-HFE2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7222 concentration 5 ug/ml.

Anti-HFE2 / Hemojuvelin Antibody (aa234-416, Biotin) - LS-C297852 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HFE2 / Hemojuvelin Antibody (aa234-416, FITC) - LS-C303427 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Search more