HFE2

Gene Symbol	HFE2
Entrez Gene	148738
Alt Symbol	HFE2A, HJV, JH, RGMC
Species	Human
Gene Type	protein-coding
Description	hemochromatosis type 2 (juvenile)
Other Description	RGM domain family member C|haemojuvelin|hemochromatosis type 2 protein|hemojuvelin|repulsive guidance molecule c
Swissprots	Q6ZVN8 Q8WVJ5 Q2PQ63 B1ALI7 Q8NAH2 Q6IMF6
Accessions	ABC40718 CAI22091 CAI22092 CAI22349 CAI22350 CAN86494 CAO00462 CAX62674 CAX86829 CEF39436 EAW71407 EAW71408 EAW71409 Q6ZVN8 AA479148 AK092682 BAC03944 AK092692 BAC03947 AK096905 BAC04890 AK124273 BAC85823 AK223575 AK290831 BAF83520 AK292742 BAF85431 AK315852 BAF98743 AY372521 AAR22390 BC017926 AAH17926 BC085604 AAH85604 DB035674 HQ447765 ADQ32250 XM_005272932 XP_005272989 NM_145277 NP_660320 NM_202004 NP_973733 NM_213652 NP_998817 NM_213653 NP_998818
Function	Member of the repulsive guidance molecule (RGM) family. Involved in iron metabolism. Acts as a bone morphogenetic protein (BMP) coreceptor (By similarity). Enhancement of BMP signaling regulates hepcidin (HAMP) expression and iron metabolism (By similarity). May cooperate with hepcidin to restrict iron absorption in the gut. Could represent the cellular receptor for hepcidin. {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
Tissue Specificity	Adult and fetal liver, heart, and skeletal muscle. {ECO:0000269|PubMed:14647275}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RGMC gene - orb90994 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

HFE2 - MBS1276578 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC017926

Human HFE2 ORF Clone(NM_213652.3) - CDCR328364 from Creative Biomart Species Human Accession NM_213652.3

Human HFE2 ORF Clone(NM_213652.3) - CDCR328365 from Creative Biomart Species Human Accession NM_213652.3

Human HFE2 ORF Clone(NM_145277.4) - CDCL165981 from Creative Biomart Species Human Accession NM_145277.4

Human HFE2 ORF Clone(NM_145277.4) - CDCL165982 from Creative Biomart Species Human Accession NM_145277.4

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone in cloning vector - HG10410-M from Sino Biological Species Human

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10410-ACR from Sino Biological Species Human

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10410-ACG from Sino Biological Species Human

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid, N-His tag - HG10410-NH from Sino Biological Species Human

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid - HG10410-UT from Sino Biological Species Human

Human HFE2 / RGM-C transcript variant a Gene cDNA Clone (full-length ORF Clone) expression ready, untagged - HG10410-M-N from Sino Biological Species Human Accession NM_213653.3

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10410-M-F from Sino Biological Species Human

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10410-NF from Sino Biological Species Human

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10410-NM from Sino Biological Species Human

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid, C-HA tag - HG10410-CY from Sino Biological Species Human

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10410-CF from Sino Biological Species Human

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid, N-HA tag - HG10410-NY from Sino Biological Species Human

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid, C-His tag - HG10410-CH from Sino Biological Species Human

Human Hemojuvelin / HFE2 transcript variant a Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10410-CM from Sino Biological Species Human

Human RGM-C ORF clone(NM_213653.3) - CDCL185975 from Creative biogene Species Human

Human HFE2 ORF Clone(NM_213652.3) - CDCR328364 from Creative biogene Species Human

Human HFE2 ORF Clone (BC017926) - CDCS417022 from Creative biogene Species Human Accession Q6ZVN8

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