HFE2

Gene Symbol	HFE2
Entrez Gene	148738
Alt Symbol	HFE2A, HJV, JH, RGMC
Species	Human
Gene Type	protein-coding
Description	hemochromatosis type 2 (juvenile)
Other Description	RGM domain family member C|haemojuvelin|hemochromatosis type 2 protein|hemojuvelin|repulsive guidance molecule c
Swissprots	Q6ZVN8 Q8WVJ5 Q2PQ63 B1ALI7 Q8NAH2 Q6IMF6
Accessions	ABC40718 CAI22091 CAI22092 CAI22349 CAI22350 CAN86494 CAO00462 CAX62674 CAX86829 CEF39436 EAW71407 EAW71408 EAW71409 Q6ZVN8 AA479148 AK092682 BAC03944 AK092692 BAC03947 AK096905 BAC04890 AK124273 BAC85823 AK223575 AK290831 BAF83520 AK292742 BAF85431 AK315852 BAF98743 AY372521 AAR22390 BC017926 AAH17926 BC085604 AAH85604 DB035674 HQ447765 ADQ32250 XM_005272932 XP_005272989 NM_145277 NP_660320 NM_202004 NP_973733 NM_213652 NP_998817 NM_213653 NP_998818
Function	Member of the repulsive guidance molecule (RGM) family. Involved in iron metabolism. Acts as a bone morphogenetic protein (BMP) coreceptor (By similarity). Enhancement of BMP signaling regulates hepcidin (HAMP) expression and iron metabolism (By similarity). May cooperate with hepcidin to restrict iron absorption in the gut. Could represent the cellular receptor for hepcidin. {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
Tissue Specificity	Adult and fetal liver, heart, and skeletal muscle. {ECO:0000269|PubMed:14647275}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse HFE2 / Hemojuvelin ELISA Kit (Sandwich ELISA) - LS-F6388 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.256 ng/ml Range 0.625-40 ng/ml

Human HFE2 / Hemojuvelin ELISA Kit - LS-F5782 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.062 ng/ml Range 0.156 - 10 ng/ml

Rat HFE2 / Hemojuvelin ELISA Kit (Sandwich ELISA) - LS-F7440 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 14.3 pg/ml Range 0.625-40 ng/ml

Mouse HFE2 / Hemojuvelin ELISA Kit (Sandwich ELISA) - LS-F10524 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 0.625-40 ng/ml

Human HFE2 / Hemojuvelin ELISA Kit (Sandwich ELISA) - LS-F12499 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.78 Range 0.625-40 ng/ml

Human RGM-C/Hemojuvelin DuoSet ELISA - DY3720-05 from R&D Systems Category ELISA Kit Prices $299.00 Sizes 1 kit (for 5 Plates) Range 0.63 - 40 ng/mL

Mouse/Rat RGM-C/Hemojuvelin Quantikine ELISA Kit - MRGMC0 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 4.46 pg/mL Range 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)

Human Hemojuvelin ELISA Kit - abx151793 from Abbexa Category ELISA Kit Sensitivity 0.062 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human HFE2 ELISA Kit - abx054860 from Abbexa Category ELISA Kit

Hemochromatosis type 2/juvenile-human homolog, HFE2, Human, ELISA Kit - CSB-E11766h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Hemojuvelin (HJV), Human, ELISA Kit - SEB995Hu from ARP American Research Products Category ELISA Kit Prices $616.50 Sizes 96 t Sensitivity 0.062ng/mL Range 0.156-10ng/mL

Hemojuvelin, HFE2, Human, ELISA Kit - E1077h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.78-50 ng/mL

Hemojuvelin, Human, ELISA Kit - E01H0066 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 2.5-50ng/mL,

Hemojuvelin/Hemochromatosis Type 2, HJV/HFE2, Human, ELISA Kit - E-EL-H1854 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Hemojuvelin, HJV, Mouse, ELISA Kit - E-EL-M0654 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Hemojuvelin/Hemochromatosis Type 2, HJV/HFE2, Rabbit, ELISA Kit - E-EL-RB1195 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Hemojuvelin/Hemochromatosis Type 2, HJV/HFE2, Chicken, ELISA Kit - E-EL-Ch2183 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Hemojuvelin/Hemochromatosis Type 2, HJV/HFE2, Porcine, ELISA Kit - E-EL-P1261 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Hemojuvelin/Hemochromatosis Type 2, HJV/HFE2, Guinea Pig, ELISA Kit - E-EL-GP0256 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Hemojuvelin/Hemochromatosis Type 2, HJV/HFE2, Monkey, ELISA Kit - E-EL-MK0324 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human HFE2 ELISA Kit - HH0247 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human HJV ELISA Kit - HH0073 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine HJV ELISA Kit - AH0073 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine HFE2 ELISA Kit - AH0247 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human HJV/HFE2(Hemojuvelin/Hemochromatosis Type 2) ELISA Kit - E-EL-H1854 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

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