ULBP2

Gene Symbol	ULBP2
Entrez Gene	80328
Alt Symbol	ALCAN-alpha, N2DL2, NKG2DL2, RAET1H
Species	Human
Gene Type	protein-coding
Description	UL16 binding protein 2
Other Description	NKG2D ligand 2|retinoic acid early transcript 1H
Swissprots	Q9BZM5 Q5VUN4
Accessions	AFP99107 AFP99108 AFP99109 AFP99110 AFP99113 AFP99114 AFP99115 AFP99116 AFP99117 AFP99118 EAW47777 EAW47778 Q9BZM5 AB052906 BAB61048 AF304378 AAK13082 AF321606 AAN39920 AK299895 BAG61739 AX772820 CAE06259 AY026825 AAK07688 AY358665 AAQ89028 BC034689 AAH34689 BG718474 NM_025217 NP_079493
Function	Ligand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. {ECO:0000269|PubMed:11777960}.
Subcellular Location	Cell membrane; Lipid-anchor, GPI-anchor. Secreted.
Tissue Specificity	Expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. {ECO:0000269|PubMed:11444831}.
Top Pathways	Natural killer cell mediated cytotoxicity

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ULBP2 / RAET1H ELISA Kit (Sandwich ELISA) - LS-F7483 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 0.055 ng/ml Range 0.156-10 ng/ml

Human ULBP2 / RAET1H ELISA Kit (Sandwich ELISA) - LS-F12119 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 12.5 Range 0.156-10 ng/ml

Human ULBP-2 DuoSet ELISA - DY1298 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 62.50 - 4,000 pg/mL

NKG2D ligand 2, ULBP2, Human, ELISA Kit - E2254h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 12.5-800 U/mL

UL16 Binding Brotein 2 (ULBP2), Human, ELISA Kit - SEL882Hu from ARP American Research Products Category ELISA Kit Prices $790.00 Sizes 96 t Sensitivity 0.055ng/mL Range 0.156-10ng/mL

Custom Human ULBP-2 ELISA - ELH-ULBP2 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human ULBP2 ELISA Kit - HU0022 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine ULBP2 ELISA Kit - AU0022 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

UL16 Binding Brotein 2 (ULBP2), ELISA Kit - MBS2023145 from MyBioSource Category ELISA Kit Prices $410.00, $610.00, $830.00, $3,420.00, $6,200.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.055ng/mL. Range 0.156-10ng/mL

Ul16 Binding Protein 2, ELISA Kit - MBS006409 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

UL16 Binding protein 2 - MBS737811 from MyBioSource Category ELISA Kit Prices $470.00, $675.00 Sizes 48 strip wells, 96 strip wells Sensitivity The sensitivity in this assay is 0.1 ng/mL.

UL16 Binding protein 2, ELISA Kit - MBS735767 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

UL16 Binding protein 2, ELISA Kit - MBS734490 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Ul16 Binding Protein 2, ELISA Kit - MBS008737 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ul16 Binding Protein 2, ELISA Kit - MBS099370 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

UL16 Binding protein 2, ELISA Kit - MBS742967 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

UL16 Binding protein 2, ELISA Kit - MBS737339 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Ul16 Binding Protein 2, ELISA Kit - MBS029003 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

UL16 Binding protein 2, ELISA Kit - MBS738127 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ul16 Binding Protein 2, ELISA Kit - MBS026475 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ul16 Binding Protein 2, ELISA Kit - MBS017778 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

UL16 binding protein 2, ELISA Kit - MBS9333371 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ul16 Binding Protein 2, ELISA Kit - MBS064129 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

UL16 Binding protein 2, ELISA Kit - MBS738443 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ul16 Binding Protein 2, ELISA Kit - MBS019855 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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